The modern ultimate practical large vehicle is the minivan. It's a vehicle form factor that is designed for maximum comfort and utility, with no compromises. If you have multiple kids getting in and out on the regular, or if you need to be able to transport lots of cargo, then there is no vehicle type that will make your life easier than a minivan.
SUVs are for people who want a minivan but are misogynistic. Crossovers are for people who consider themselves better than the SUV people but haven't fully purged their misogynistic priors. Hatchbacks are for people who would get a minivan if they needed one but can't justify owning a vehicle of that size.
Full size vans and trucks are also an option if your needs truly justify the increased size. If you're in true "bang for buck" practicality mode, look for former fleet vehicles being sold off. They'll have a lot of use but they were probably well taken care of.
startlingly accurate
A bike does fit, but you can only bring one friend.
