News

All of a sudden? You mean it gets worse??

It was nice knowing you.

Obsolete

Read further in that paragraph:

Researchers assessed 135,000 different molecules (RNA, proteins and metabolites) and microbes (the bacteria, viruses and fungi living in the guts and on the skin of the participants).

Also, see the previous article in Nature linked in the article. That study looked at fewer proteins, but had over 4,000 participants.

My favorite part of science discourse will always be people self-reporting how little they understand science the math behind statistics by complaining about sample sizes that have nothing wrong with them

43: chuckles, I'm in danger.

Lol literally my thought.

Woah there, save something to degrade in another 13 years.

RIP

Oh man, 30 was the best.

Sorry to hear yours isn't.

I started playing Ultimate Frisbee again at 44 and quickly regained most of my youthful speed and jumping ability (and my tendency to huck). So for me it was like the opposite of this article's contention. Age 52/53 was a lot worse as that's when I started getting arthritis.

1st heart attack at 49...

I just got progressive bifocals. It was nice to be able to read my watch properly again, but not so nice to have to look down whenever I'm going up or down stairs and to have to move my head around all the time to see all the real estate on my monitor since it's 27".

I know what you mean. I make old people noises now, when I stand up from a low couch or sth.

Good on you, I've read elsewhere that the better shape you can be in prior to years of decline, the better you handle the natural aging process. I don't need to do anymore marathons, they're too hard on my knees, but running/biking and body-weight exercises are part of my attempt to stave off the inevitable.

This article is reminding me of a study a few years back that suggested that (provided you're otherwise healthy and able bodied) you can get into any level or shape you want (if you put in the work of course) up until 60-something. Then you hit an age wall where about the best you can do is maintain what you've got. Suggesting that countering that 40-something aging event by pre-gaming for the 60-something aging is a smart plan.

One morning you'll wake up and every bone in your body will pop simultaneously. Then while you lay there aching you'll let out a 6 mimutes and 20 second fart that doesn't have a happy ending.

Yeah West in his seminal "Scale" kind of corroborates the whole story.

It seems, though, that the molecular changes you are undergoing do not immediately translate into increased mortality, so you're going to have several more years of - presumably - feeling well until the big drop-off starts for all of us at about 60.
BTW, because of its wide range of topics, its solid scientific underpinnings and its excellent intellectual accessibility, this is one of two books I positively think should be taught at any school, the other one being Solé's "Phase Transitions."