arnt alot of people found to have the cancer syndrome, like lynch since cancer found under 50+ are often people with genetic mutation for it, rather than sporadic caused.
this post was submitted on 12 Mar 2026
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Got my first colonoscopy coming in two weeks.
Fingers crossed.
Pro Tip:Whisk(e)y is considered a clear liquid. And if you are lucky, you can have your colonoscopy at a teaching hospital and get to have a train run on your ass by 3 or 4 med students practicing on you while you are sedated.
Good Luck! I'm pullin' for ya!
plus side of colonscopy any polyps they find they cut asap and biopsy it, if you're younger than 45, you might be able to ask for genetic testing for cancer syndromes.
Some populations are more at risk than others. Alaska Natives have the highest documented colorectal cancer mortality in the world, but Siegel said that, because the total number of Alaska Natives is so small, it’s hard to get funding to study why.
I don't doubt that it is difficult to get funding (especially now), but seems kind of dumb.
If anything such a small population in a relatively isolated environment seems like it would allow researchers to better control variability. Unless it's strictly a genetic risk factor, it would seem that any significant environmental risk factors they find could actually be studied in bigger heterogenous populations, right?
Eat shit, die from it, i see no problem here.
If it's not one type of cancer it's another. I'm certain a scientist found a way to kill cancer cells and the pharmaceuticals buried it. Cancer and flu are highly profitable businesses.
flu is pretty much a given, because it has very high mutation rates, so its hard even get a vaccine for it every year. covid, flu, HIV have one of the highest mutagenic rates.
Just coming back now after my stage 2 surgery...
Here's the thing, my symptoms didn't even seem to be colon or cancer related. I was having fatigue, out of breath, tired all the time.
Not unusual for a dude with 2 heart attacks and congestive heart failure, but the blood work was showing anemia, low red blood cell count, low hemoglobin, small red blood cells.
Something was chewing up the blood, but it wasn't clear what.
Enter the colonoscopy/endoscopy... 17 polyps, 2 of which unusually large (20mm and 30mm). But NOT cancerous. Not even pre-cancer.
Rule of thumb is anything more than 5 or bigger than 5mm, you get re-checked 6 months later.
6 months later... 6 new polyps, and a 20mm monster that was full blown invasive stage 2 cancer.
Went under the knife 2/19, they pulled my sigmoid colon and all the related lymph nodes. If the cancer got into the lymph system, that's stage 3 and cause for chemo.
Well, they got it all! No stage 3! But I've kinda been rolling around in bed ever since. 2 more weeks of recovery.
That's awesome! I hope you have clear sailing and everything is rainbows from now on!
Working on it, Friday was a tough day. Lots of pain and feeling sick. 🙁 Pretty much lost the whole day.
But our kid and his wife came over to help out and that was good!
did you ever get genetic testing, if you had something lynch syndrome?
Genetic testing was required after the first colonoscopy and they checked, I dunno, 180? 200? known gene markers for cancer?
I was clean on all of them, but they turned up one abnormality that is flagged as "unknown" for cancer risk:
"FLCN Variant, Unknown Significance: p.G66E
Variant of Unknown Significance Detected"
I can't remember what all that means, but it's a crazy small variant. One section of one gene, they found a "G" where they expected a "C", or the other way around, something like that.
hey, good luck on recovery. I don't know much about cancer recovery, but i've had so many gastro surgeries that they named a room after me at the hospital on the trauma ward. if you ever need a listening ear, send me a dm.
Between my wife and myself, we're in the same boat with the Emergency Room.
"Oh, room 13? Yeah, we know where that is..."
have they gotten on your case for muting the iv pumps yet? they're so easy to mute and i don't need hearing loss, right?
We bug them and make them do it until they get sick of hearing from us and mute it themselves. LOL.
When you're down to the last 100 ml of saline and reprogram the pump to slow down so it won't run out so the alarm doesn't go off and then you page your nurse, just FYI that's too far. That's the one that really got me in trouble
God damn, good catch! Wishing you the best of luck in your recovery and your remission.
Yeah, I tell this story because going from 0 to stage 2 in 6 months is terrifying.
Yeah that's nuts. I've only heard of that in the super aggressive cancers like glioblastoma
AML is quite similar very aggressive, other rare type of leukemias can do that.
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I got diagnosed last year at 30 years old. I had lower abdominal pain that lasted a little over a month that I figured was IBS from a traumatic life event that recently happened. It was slowly improving until one day I woke up in extreme abdominal pain. There wound up being a mass at the very start of my large intestine.
The doctors found no obvious reasons as to why it happened- no family history, no substance abuse, no excessive energy drink or alcohol consumption. I now make a large effort to cut out as much processed food in my diet as I can.
Also up your fiber. Low fiber is linked to increased colon cancer risk and most Americans get well below their recommended daily dose.
Glad you're still kicking with the living though and good luck
I doubt seriously that this epidemic is a fiber problem. This generation is ingesting something we shouldn’t be. I’d suspect plastics, but we’ve been eating out of Tupperware since the 1950s. Maybe PFAS? Maybe a newer plastic formulation? A more recent pesticide like Roundup? Some preservative we didn’t start using until the 1990s?
I impatiently await the scientific study that reveals the right link.
Have a gander at 4 known digestive carcinogenic compounds that are used on american food that are banned everywhere else.
Add in the known carcinogenic effect of over processed and fried foods we are probably on to something.
A single data point but Owsley famously wouldn't touch fiber and only ate raw meat all of his life and he didn't die of colon cancer.
nitrates are in most cured meat, also celery salt as well if you are looking for nitrate free products, but it has celery salt, since celery acumulates nitrates naturally. some people can actually smell and taste the nitrates easily, its a very awful smell and the taste too.
You're going to be disappointed because there's almost never any one thing.
We know, for a fact, that lower fiber intake increases colon cancer risk. So if you lower fiber intake while also increasing ingestion of something that increases risk, well how do you say which is the right link?
Oh, this goes with all the normal caveats of studies still need to be done, I'm not a doctor just try to stay informed, etc, but some more recent studies have shown a link between excess sugar intake and increased colon cancer risk. The sugar source doesn't seem to matter so much as amount (so honey vs high fructose corn syrup doesn't matter). We've been slowly adding more and more sugar to everything, at least here in America, so shrugs eat less sweets and more beans.
I have to say, I don't think it's going to turn out to be any one thing, but it's probably a lot of somethings that are different for Gen X and Millennials vs Boomers.
Maybe it's related to eating processed food during some kind of critical window that occurs earlier in life (and processed food just didn't exist to the extent that it does now when my dad was growing up), but comparing the current diets of most boomers to most millennials, I have to say I know a lot of boomers that have continued eating like America did throughout the 90s, while a lot of millennials began making healthier food choices.
Like this seems to be at least one reason that the fast food industry is dying, especially now that it's not even cheap anymore.
I know a lot of boomers that have diets like my dad, and good lord that man ate bologna and other processed meats and foods non stop when I was growing up. He also smoked for several years. He's coming up on 73 and cancer free so far. Granted that's an n of 1, but it also seems there was a reason it was trendy for boomers to scoff at millennials for enjoying their avocado toast for breakfast instead of bacon and eggs.
For people over age 65 colorectal cancer is “continuing to decline rapidly by more than two percent a year”, Siegel said, whereas for younger people, it’s jumped from the fifth to the first leading cause of cancer death since the 1990s.
There seems to be little doubt it is hitting earlier for younger generations, but decreasing in the boomers that were feeding us the processed foods and also eating it over the same length of time we were growing up. Is it just because of screening?
It's also not like it's only hitting younger poor people. Even Kate Middleton was suffering from it a couple of years ago. Granted you never know how somebody eats, but given the relationship between income and food desserts, I would expect income level to be a stronger predictor.
Some populations are more at risk than others. Alaska Natives have the highest documented colorectal cancer mortality in the world, but Siegel said that, because the total number of Alaska Natives is so small, it’s hard to get funding to study why.
Also found this to be really interesting. There are very high poverty rates in Alaska, but junk foods and processed foods can actually be cost prohibitive since everything has to be imported. Also would expect less fast food consumption in Alaska for similar reasons.
could be genetic bottleneck population? limited diversity increased for lethal alleles to appear in a small population.
There's a ton of sugar in canned beans, especially baked beans.
sugar isnt usually increasing the rate of colon cancer, makes you susceptible to diabetes type 2.
Baked beans sure but I just checked the can of black beans and the can of chickpeas on my shelf. Only thing in ingredients is beans, water, salt.
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teflon maybe? idk. maybe it's a left handed type thing where now we notice, or we all just died and/or suffered and were just "picky eaters" before.
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Got a test coming up in about a month for the first time closing on 48. It's such an obnoxious thing to try and deal with because nobody wants to talk about why their guts and ass are all messed up.
I think the best way around it is to recognize that it's just like any other medical thing. Throat hurts you go get it looked at, why not the other end of the path too.
Rectal bleeding, bloody stool, and narrow poops. You might also get intermittent constipation with no apparent cause, and a feeling like something is constricting your intestine.
Unfortunately it sounds like this isn't because other cancers have fallen, just that this has increased.
This is also a function of the Manosphere bro diet and the trend of only eating protein. Those diets slow digestion and allow carcinogenic metabolites from gut bacteria to accumulate in the colon.
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