Another fun-ish, kinda fucked up, weird story... There's a woman, Henrietta Lacks, who had a biopsy for her cervical cancer in January of 1951 before passing in October of that year. These cells were found to be incredibly resilient and quick to replicate. Most cells only lasted a few days before dying, but hers seemed to be functionally immortal under controlled lab conditions.

So, unbeknownst to her as consent wasnt required for such things at the time, her cancer cells were cultured and grown into large samples to be used in research. Those samples were split off and passed off to other labs. They've since spread around the entire world for a ton of research and commercial purposes.

They were used in the development of the polio vaccine, for example, as well as having been used in research on cancer (obviously), AIDS, the effects of radiation and toxic materials, gene mapping, etc. They are used to test safety of cosmetics as well. Approximately 11,000 patents involve these specific cancer cells.

In the 1970s, there was an incident where these cells contaminated other cell cultures, so the researchers needed DNA samples from the Henrietta's family to differentiate her cells from the others. This is the first time anyone in her family learned that her cells had been used in research at all, let alone that her cells were being cloned and used in research and commercial product development across the entire world. It became a legal issue after this, and after a couple decades of litigation, it made it to the Supreme Court of California where they ruled that "discarded biological materials" is no longer ones property and could be commercialized freely. They continue to occasionally fight against aspects of her cells' usage, and they're are health privacy concerns for her family as well, but results have been mixed for them.

Henrietta the person died in 1951 at age 31, but her immortal cancer cells which still contain her full DNA sequence continue to live to this day, 75 years later. One source claims that as much as 50 million metric tons of tissue has been generated from these cells.

[–] mycodesucks@lemmy.world 13 points 3 hours ago* (last edited 3 hours ago)

HeLa is extremely interesting, but still requires humans to cultivate her cells.

Canine transmissible venereal tumor however, is an immortal, contagious dog tumor from a dog thousands of years ago that evolved into its own lifeform - a sexually transmitted parasitic cancer - that has continued to this day to spread from host to host. Yet, genetically, it is still "dog".

Anyway, this is my answer when the job interviewer asks me about long-term goals.

[–] a_wild_mimic_appears@lemmy.dbzer0.com 3 points 3 hours ago

I worked with HeLa cells as a molecular biology student. The ethics weren't a great look, and I'm happy that today there has to be informed consent for stuff like that.

Without having an immortalized cell line like this genetics would have taken even longer to get going tho, and she's actually one of the few people whose genes will be preserved for near eternity. Creepy, but it's closer to actual immortality than any of us will ever be.

[–] 14th_cylon@lemmy.zip 13 points 5 hours ago (1 children)

In the 1970s, there was an incident where these cells contaminated other cell cultures, so the researchers needed DNA samples from the Henrietta's family to differentiate her cells from the others.

I don't understand. First, what was the point? I doubt there was a way to split the sample attacked by a cancer cells, they probably weren't going to recalibrate the transporter and untuvix them.

Second, weren't there thousands of the copies of the sample? Why wouldn't they compare it to one of them, instead of bothering the family?

[–] kryptonianCodeMonkey@lemmy.world 9 points 5 hours ago

That confused me as well. The stuff I read didn't elaborate on how that would help.