Opal Sandy from Oxfordshire in the UK is the first patient treated in a global gene therapy trial, which shows “mind-blowing” results. She is the first British patient in the world and the youngest child to receive this type of treatment.

Opal was born completely deaf because of a rare genetic condition, auditory neuropathy, caused by the disruption of nerve impulses travelling from the inner ear to the brain.

Within four weeks of having the gene therapy infusion to her right ear, Opal responded to sound, even with the cochlear implant in her left ear switched off.

Clinicians noticed continuous improvement in Opal’s hearing in the weeks afterwards and at 24 weeks confirmed close to normal hearing levels for soft sounds, such as whispering, in her treated ear.

Now 18 months old, Opal can respond to her parents’ voices and can communicate words such as “Dada” and “bye-bye.”

"These results are spectacular and better than I expected. Gene therapy has been the future in otology and audiology for many years and I’m so excited that it is now finally here," says Professor Manohar Bance, an ear surgeon at Cambridge University Hospitals NHS Foundation Trust and chief investigator of the trial.

Professor Bance hopes that this is the start of a new era for gene therapies for the inner ear and many types of hearing loss.

cross-posted from: https://kbin.run/m/world@lemmy.world/t/410267

More than 200 people with diabetes have been injured when their insulin pumps shut down unexpectedly due to a problem with a connected mobile app, the US Food and Drug Administration said Wednesday.

Hospital leaders say the health system won’t be ready if the avian flu that’s infected American dairy cattle becomes widespread among humans.

In discussing a hypothetical scenario, the hospitals have struck a different tone than the Biden administration. It says the risk is currently low to most people and that agencies are closely monitoring for any sign of danger to Americans.

Still, hospital officials told POLITICO they’re dismayed that they don’t feel better prepared, just four years after Covid-19 caught them unawares. They’re not confident that the health care system — including the government agencies that have wound down Covid responses — can avoid the missteps around tests, bed space and communication that plagued the last public health emergency, should this strain of flu, H5N1, become more of a threat.

cross-posted from: https://lemmy.ca/post/20510991

Sick notes place an unnecessary burden on doctors and patients, physicians' organizations say

Family doctors frustrated with writing sick notes have created a template letter for patients to give to their employers, explaining that the notes place an unnecessary burden on physicians during an ongoing primary-care crisis.

They are also calling on the province to restrict when and how employers can ask for sick notes.

Many family doctors spend between 20 and 30 per cent of their day doing paperwork, Ali says, and filling out sick notes only adds to that.

Also, having to leave the house to get a note does not allow the sick person to rest, Ali said, and the task is made even more difficult for those who don't have a family doctor and have to wait in walk-in clinics. "A person who feels under the weather — the last thing they want to do is possibly get on a bus, or into their vehicle, or ask someone for a ride to go to their doctors office," said Ali.

As of 2023, employers in Nova Scotia are only allowed to request a sick note if the absence is more than five consecutive work days.

New legislation in Ontario, meanwhile, will force employers to scrap sick notes for the three days of provincially mandated annual sick leave. The Ontario government is moving to ban sick notes for short-term illness, in an effort to cut down on paperwork for family doctors.

In a statement sent to CBC News, B.C.'s Ministry of Labour said employers are able to request "reasonably sufficient proof" of illness, but are encouraged to be thoughtful about when they request sick notes.

It did not respond to questions about whether it is considering legislation to ban or restrict asking for sick notes.

Sorry that's being referenced in this one: https://www.nbcbayarea.com/news/health/nurses-kaiser-sf-protest-ai/3516888

Walmart had made a big push into health care in recent years, opening clinics next to its superstores that offered primary and urgent care, labs, X-rays, behavioral health and dental work — Arkansas, Florida, Georgia, Illinois, Missouri and Texas. Walmart believed it could use its massive financial scale and store base to offer convenient, low-cost services to patients in rural and underserved areas that lacked primary care options.

But the announcement is an abrupt reversal in Walmart’s strategy and may leave a gap in health care access, particularly for lower-income patients without insurance who relied on the centers. Walmart also said it will end virtual health care services. 99 Cents Only Stores, founded in 1982, announced Thursday that they will close all 371 of its stores. Nearby stores include Visalia (pictured), Tulare, Hanford, and Porterville.

Related article Dollar stores are shutting down across America. They did this to themselves

“One of unique things was they were focused on stores located in underserved communities. It’s disappointing that Walmart wasn’t able to make it work because these patients need care and don’t have as many options,” said Ateev Mehrotra, a professor of health care policy and medicine at Harvard Medical School who researches retail health clinics.

Walmart said it was a “difficult decision,” but its health care push was not profitable for the company because of the “challenging reimbursement environment and escalating operating costs.”

“We determined there is not a sustainable business model for us to continue,” the company said.

"Researchers at the Technical University of Denmark (DTU) and Lund University, Sweden, have used enzymes produced by a common gut bacteria to remove the A and B antigens from red blood cells, bringing them one step closer to creating universal donor blood."