A little more than run-of-the-mill, they've represented victims of several mass-casualty disasters such as the Deepwater Horizon spill, and other high profile cases:

https://www.lawdragon.com/lawyer-limelights/2025-04-08-blowing-away-the-competition-arnold-itkin-turns-twenty

-$8B verdict against Johnson & Johnson

-$2.25B verdict for a Roundup cancer victim

-$860M verdict for victim of fatal crane accident

-$557M verdict against Union Pacific

Also, cited from a reddit comment, apparently they have been engaging in political maneouvers against Republicans: https://www.houstonchronicle.com/opinion/outlook/article/dick-weekley-texans-lawsuit-reform-gop-power-21250759.php

This year, two of Texas’s most prominent Democratic trial lawyers — Kurt Arnold and Jason Itkin — have begun writing six-figure checks to Republican candidates in key primaries. They recently funded their PAC with a $10 million donation that is now being used to influence GOP races. They’ve discovered they don’t need to win general elections to block reform — they only need to shape who gets on the ballot. By posing as allies of the right, they can protect their legal privileges while claiming to defend Texans’ rights.

And for the moment, the tactic appears to be working. Several Republican House members who joined Democrats to weaken a major lawsuit-reform bill in Texas during its 2025 regular legislative session later received a campaign contribution from that same PAC. Arnold & Itkin’s namesake partners have long donated millions to Democrat candidates and causes – including more than $1 million to a George Soros–linked PAC that ran ads calling on voters to “Stop MAGA Republicans.” Yet now they happily fund Republicans in Texas, so long as those Republicans promise not to rein in lawsuit abuse.

I try not to egg on too much conspiratorial thinking, but it is kind of an interesting case here. This was during a winter storm in the area too, which would make people think less of the accident, but according to r/aviation conditions were normal and pilots sounded unsure why they would have crashed. There were no issues for other flights at the airport or in the region.