this post was submitted on 01 Sep 2025
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traaaaaaannnnnnnnnns

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[โ€“] rtstragedy2@hexbear.net 7 points 2 months ago (5 children)

concerns about long term side effects of medicationso when i switched to CPA (cyproterone acetate) at the start of this year my doctor mentioned something about there being some risk of "benign brain tumours" as a side effect of the medication, has anyone heard of this?

[โ€“] CrookedSerpent@hexbear.net 8 points 2 months ago

This is a well known side effects of CPA, it's not recommended for long term use. But you should be probably fine for short term use at the low doses required for it to be effective.

[โ€“] 0x2640@hexbear.net 7 points 2 months ago (1 children)

known side effect but only at high dosages over long periods

its like how every medication in existence has a "may cause heart attack" or whatnot warning, just because it can happen doesnt mean it will

[โ€“] rtstragedy2@hexbear.net 4 points 2 months ago

thanks yeah fair it'll probably be a couple years before I can get off it I'll have to talk to doc about risk again since despite that I am getting some anxiety about it suddenly

It's a real side effect and it's more likely to happen with higher doses, so a lot of trans women who need to use CPA take a low dose, ~6mg/day. A lot of people don't actually need to use an antiandrogen if they're on a high enough dose of estradiol - this is easier to achieve with injections.

[โ€“] TerminalEncounter@hexbear.net 5 points 2 months ago (1 children)

Yeah, prolactinoma. My prolactin levels are higher on it. Im on a quater tab every week so I think my prolactin is higher cause of stress more than cyproterone

[โ€“] rtstragedy2@hexbear.net 3 points 2 months ago* (last edited 2 months ago) (1 children)

a quarter tab every week? wow, I'm on quarter per day and I was told the half life was like 36 hours so it made sense to take it every day to me (as prescribed)

[โ€“] TerminalEncounter@hexbear.net 3 points 2 months ago (1 children)

I know!! I asked if I could just do monotherapy at this point but he insists on the once a week thing. Hes the one who went to medical school but I seriously just wanna drop it if its a quarter tab (theyre annoying to break that far) once a week.

[โ€“] sodium_nitride@hexbear.net 5 points 2 months ago

benign brain tumors sounds wild outta context.