xep

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[–] xep@discuss.online 1 points 4 days ago (2 children)

Things I found particularly interesting:

Atherosclerosis, or plaque, is not a focal disease. It’s a systemic disease. If you’ve got it in one artery, guess what? You’ve got it in every artery—and you may think you don’t.

A bit terrifying.

Why am I stressing this? Because if you don’t want to develop plaque, don’t want plaque progression, and don’t want the consequences of plaque formation and rupture, you need to know the cause. It’s inflammatory. It’s not linear. It’s not just a scar that keeps growing. It cracks, repairs, cracks, repairs. It’s all related to inflammation. What is your inflammatory status? We are becoming increasingly inflammatory as humans. That’s why this happens. The body reacts, and you get inflammation.

Plaques are both caused by inflammation and inflammatory.

There are two parts to this whole problem. One is plaque formation and plaque rupture—that’s all about the plaque. The next is your blood. If your blood is clotty and your platelets are very jittery, you’re going to get a big blood clot. It’s as much a hematological event as it is an inflammatory process. There are two parts to this equation. That’s why we started paying more attention to the condition of your blood. Do you have clotty blood? Because if you rupture a minor plaque, you can get a big blood clot.

I wonder if grounding, which can decrease the viscosity of blood, can help? Blood donation also helps.

With aggressive lifestyle, dietary, and environmental changes—reducing toxicity, improving your food, and everything else—you can regress it. But the extent—probably the percentage stenosis—is likely very low. That means you can reduce it by maybe 10%.

Unfortunately it seems that lifestyle changes cannot reverse plaque entirely, and it also has to be managed by reducing inflammation as much as possible.

[–] xep@discuss.online 2 points 4 days ago* (last edited 4 days ago) (1 children)

The vast majority of the content on there is a conservative echo chamber.

TIL. It's always rather amusing as someone outside of America that posts containing factual information get downvotes purely based on the perceived alignment of the subject on the zero-nuance American Political Spectrum. I block ads, so I wouldn't know.

[–] xep@discuss.online 3 points 4 days ago

Really curious about what this leads to. We also know that plants can signal each other via the mycelium, they have awareness of their surroundings and events, just not in the same way we do.

[–] xep@discuss.online 1 points 4 days ago (3 children)

What about Rumble? GN is on there and directly supportable.

[–] xep@discuss.online 2 points 5 days ago* (last edited 5 days ago) (1 children)
  • Why I don’t find expert opinion compelling

I DEMAND to see the source studies the opinion is based on, and I will apply the same evaluation to that. If the expert opinion is based on a volume of cherry picked epidemiology then I don’t think much of the expert opinion. This includes the WHO IARC.

You’re being very nice by not mentioning that many experts are bought and paid for by corporate interests. It’s important to look at who the experts are and what organizations they’ve done the studies or are speaking for in the context of the larger, more influential organizations that they are associated with in any way.

[–] xep@discuss.online 2 points 5 days ago* (last edited 5 days ago)

moved post to respond to the right comment

[–] xep@discuss.online 3 points 5 days ago* (last edited 5 days ago) (1 children)

I can only speak from my own experience, but self-experimentation was a part of it, as well as reading science that isn't just nutrition science. For example, we know that plants contain toxins, since it's a fact. We know that thermally stressing PUFAs results in various oxidation end products, again because this is a fact. We know that ultraprocessed foods are by and large made up of plant matter. In that case it would make sense that if the hypothesis for carnivore is that I wouldn't need any plant matter in my diet, then I could avoid all these things. I decided to test that by doing an experiment on myself to see if that's true that I could just not eat any food derived from plants for a while.

At the time I was already on a LCHF whole food diet with moderately high fat so I knew I could switch slowly without affecting my gut too much, but to be safe, I had blood panels done and informed my friends that they should tell me if I looked even vaguely sick in that period of time. I was also not going through any stressful events other than this, so I would be able to minimize other confounding effects caused by hormonal changes.

My results were that I was informed by the same friends that I looked the best I'd ever been, I lost ~5 kgs of body weight (unfortunately only BIA and not DEXA scan, so I can only guess that it was mostly fat/water) and that my HDL went up, but it went up alongside my LDL levels. My sleep quality improved and my stiff shoulder resolved.

The most obvious and easiest test for me I think would be fiber and constipation. You can try that self experiment easily in 30 days, I don't think there's much danger there.

[–] xep@discuss.online 2 points 6 days ago* (last edited 6 days ago) (1 children)

I find that remarkable considering the fact that astronauts would eat high protein foods to minimize their bowel movements because the human body will efficiently absorb highly bioavailable proteins and fat (e.g. from animal sources) it consumes. Considering human feces are 75% water and the remaining 25% are primarily bacterial biomass and plant matter, my guess is the carnivores you know have just started the diet and have upset their stomachs with the sudden change.

[–] xep@discuss.online 3 points 6 days ago* (last edited 6 days ago) (1 children)

Thank you for linking her talk about the paper! It gives it so much more context. It's clear now that they studied a cohort who had already developed some brain network instability, and used exogenous ketones to induce ketosis in the participants. Dr. Lily does mention a ketogenic diet as a means to get into ketosis as well.

[–] xep@discuss.online 2 points 6 days ago (1 children)

Nick Norwitz found that plaque predicts more plaque, but this seems to offer some hope that it's possible to reverse some of that with diet. It's curious that some of the quantitive analysis would have conflicting results, though.

[–] xep@discuss.online 5 points 1 week ago* (last edited 1 week ago)

Can't wait for the year of the vibe coded OS.

[–] xep@discuss.online 8 points 1 week ago

Isotopic testing shows that early humans primarily subsisted on herbivores and small game, including fish. Please refer to this study for Europe.

Early modern humans also appear to have regularly hunted large herbivores (55–57), but there is also evidence for the use of small game, including fish at some of these sites (15, 16).

Or this study, also from Nature, again studying the first modern humans and late Neandertals in Europe:

based on stable isotopes, the mammoth seems to contribute the major part of the dietary protein of humans in a time range between 50,000 and 30,000 years ago and across wide areas spanning from SW France11 to the Crimean Peninsula53 (Fig. 6, Supplementary Fig. 5–8).

It is inaccurate to state that humans did not eat much meat prior to modern times.

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