When you need speed in Python, after profiling, checking for errors, and making damn sure you actually need it, you code the slow bit in C and call it.
When you need speed in C, after profiling, checking for errors, and making damn sure you actually need it, you code the slow bit in Assembly and call it.
When you need speed in Assembly, after profiling, checking for errors, and making damn sure you actually need it, you're screwed.
Which is not to say faster Python is unwelcome, just that IMO its focus is frameworking, prototyping or bashing out quick and perhaps dirty things that work, and that's a damn good thing.