this post was submitted on 03 Jul 2026
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[–] frongt@lemmy.zip 137 points 3 weeks ago (5 children)

"Biosynthetic gene mining of the L. asiatica genome found no close hits with any genes known in the production of mushroom psychoactive compounds," write the researchers in their published paper.

"This supports our hypothesis of the presence of a novel unidentified metabolite responsible for the unique hallucinogenic properties of L. asiatica."

Yeah. No known hallucinogens.

[–] DougPiranha42@lemmy.world 33 points 3 weeks ago (1 children)

Exactly. Or even- no known hallucinogens synthesized by their canonical biochemical pathways by enzymes expressed from the host species genome.
The OG hallucinogen, ergot, is ingested by eating wheat. If one presumed that the substance is made by wheat, if would be really tricky to find the genes for its synthesis, because the hallucinogen is made by mold growing on the wheat.
It’s very rare you can draw a strong conclusion from negative results.

[–] boydster@sh.itjust.works 15 points 3 weeks ago (2 children)

Rye is the most common place ergot grows, which is another common bread grain. I am not disagreeing with your post, and ergot can grow on wheat too, just pointing out that rye is a much more common source of egot contamination.

[–] webghost0101@sopuli.xyz 7 points 3 weeks ago* (last edited 3 weeks ago) (1 children)

I dont really know these things but i always just assumed rye (and barely) was just a kind of wilder less domesticated wheat.

[–] gandalf_der_12te@feddit.org 4 points 3 weeks ago

all cereals are related rather closely

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[–] WoodScientist@lemmy.world 58 points 3 weeks ago (5 children)

Maybe it's not a hallucination at all. Maybe the mushroom is actually an anti-hallucinogen. It suppresses the hallucinations that normally prevent us from seeing the tiny people.

[–] Arghblarg@lemmy.ca 8 points 3 weeks ago (4 children)
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[–] cattywampas@lemmy.world 51 points 3 weeks ago (4 children)

Well it does contain a psychedelic drug, just not one that we've identified yet.

[–] CannonFodder@lemmy.world 25 points 3 weeks ago (3 children)

You don't know that. Maybe it just disables the tiny people filter we normally have.

[–] acosmichippo@lemmy.world 7 points 3 weeks ago

that would be a psychedelic drug.

[–] 4am@lemmy.zip 5 points 3 weeks ago

More fnordposting

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[–] webghost0101@sopuli.xyz 8 points 3 weeks ago (8 children)

It doesn’t need to be, there is reasonable proof that humans and other mammals naturally synthesises (trace amounts off) dmt, which are presumed to be used and broken down incredibly quickly. We still don’t know why, what its used for or have hard proof where its produced (pineal gland is main suspect for having all ingredients in theory)

In theory something could trigger an effect that stops it from breaking down or produce it at a faster rate, therefore triggering psychedelics effects with out the consumed substance containing anything psychedelic itself.

Dmt is known for seeing (machine) elves, does not sound that far away from seeing mini people.

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[–] gnufuu@lemmy.ca 42 points 3 weeks ago* (last edited 3 weeks ago) (2 children)

Lanmaoa asiatica

My sincerest apologies. I know the way out.

[–] dohpaz42@lemmy.world 6 points 3 weeks ago

I had that mower. It’s a good mower. It definitely could do the job.

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[–] rizzothesmall@sh.itjust.works 35 points 3 weeks ago

they found no close matches to genes associated with psilocybin or ibotenic acid, two well-known mushroom hallucinogens

None that we already know about, not the same as none

[–] DanceMomsSavedMe@lemmy.zip 31 points 3 weeks ago (41 children)

Can't wait for it to become known so governments all across the world can throw you in a prison cell and ruin your life for it like the other known hallucinogens.

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[–] Kolanaki@pawb.social 27 points 3 weeks ago* (last edited 3 weeks ago) (6 children)

They're just enabling you to see the fae that are always there. DO NOT GIVE THEM YOUR NAME, NO MATTER WHAT!

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[–] GreyShuck@feddit.uk 26 points 3 weeks ago (2 children)

Regardless of the actual metabolite responsible, this does raise the question of whether, if any other species consume them and are susceptible, they see tiny versions of their own species?

[–] magnue@lemmy.world 12 points 3 weeks ago (2 children)

I always wonder if the cows get high. On the right day it's like daisies in summer and they're just munching grass all day.

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[–] yakko@feddit.uk 10 points 3 weeks ago (1 children)

Now that's a question. How to test it?

[–] Catoblepas@lemmy.blahaj.zone 4 points 3 weeks ago (1 children)

Monkeys seem like a good place to start. Similar enough to us to see if it’s unique to humans, small enough to not start ripping someone’s face off if it goes badly.

[–] yakko@feddit.uk 5 points 3 weeks ago (7 children)

Yeah but how do you get an experimental result from them?

[–] DougPiranha42@lemmy.world 7 points 3 weeks ago

Mackaques love touchscreens, amd can be trained to do complex tasks on tablets placed in their enclosures.
You make a test where they need to press a button when and only when they see tiny monkeys that you can project on a screen or on their floor.
Then you give the drug at various concentrations and placebo, and see if there is a dose dependent increase in the monkeys indicaions of mini monkeys.
Then you can repeat the experiment after treatment with antipsychotic, if it prevents the mini monkey reporting, you already have a hint at the mechanism.
Any nonhuman primate lab can do this from 1-2 million dollars, should we start a go fund me?

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[–] WhosMansIsThis@lemmy.world 20 points 3 weeks ago (1 children)

They finally found it. The Blue Angel mushroom really does exist...

[–] nforminvasion@lemmy.world 7 points 3 weeks ago
[–] errer@lemmy.world 20 points 3 weeks ago (2 children)

Well yeah, these guys live there

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[–] CheeseNoodle@lemmy.world 20 points 3 weeks ago (2 children)

Potentially (potentially doing a LOT of heavy lifting here) unethical, make a reasonably comfortable tiny person cell, take the mushrooms, put a tiny person in the cell. A second person who is completely unaware of the previous events takes the mushroom and we see if they can see the same tiny person still in the cell.

[–] datavoid@sh.itjust.works 7 points 3 weeks ago

Collect enough of them in their own cells and we can battle them like Pokemon!

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[–] SunshineJogger@feddit.org 18 points 3 weeks ago (2 children)

No matter what it is, it is fascinating in its own right that it has such a specific visual effect on users.

Maybe this mushroom was very common once and is the source for folk tales of all sorts.

I mean there are truly a lot of old stories involving tiny people.

[–] mPony@lemmy.world 5 points 3 weeks ago

There are also a lot of old stories about people seeing tall slender alien-like creatures. I wonder if there's a substance that causes that.

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[–] rain_enjoyer@sopuli.xyz 16 points 3 weeks ago

Clickbait headline, the primary object of that study was to figure out phylogeny of these mushrooms. finding no known genes associated with known hallucinogens is a bonus and pretty useless info because the compound responsible for this activity is not known, how do you know how it's made then

[–] deegeese@sopuli.xyz 15 points 3 weeks ago

Awkward? Unexpected results are the building blocks of science!

We learned a new question to be answered.

[–] chewypoops@lemmy.world 12 points 3 weeks ago

I know that most people describe these hallucinations as unpleasant, but I do kinda want to know. I wanna meet those little guys.

[–] nailingjello@piefed.zip 11 points 3 weeks ago

Wasn't this part of the plot of the TV show Common Side Effects ?

Good show btw.

[–] Olgratin_Magmatoe@slrpnk.net 6 points 3 weeks ago* (last edited 3 weeks ago)

Misleading title aside, these mushrooms sound really cool. It's a shame they're so hard to find.

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