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just some dice I threw around. nothing to see here
(lemmy.blahaj.zone)
Alt text: Five dices. Top left corner is a three, top right corner is a six, bottom left corner is also a six and bottom right corner is two threes forming a straight angle.
I am almost certain the only reason it ever blew up was because it's a pretty strong comic, alone, but the fact it can be represented by just a few lines such that nearly any 4 images can become a reference to the comic makes it highly memeable.
It also became memeable and noteworthy because it's it's drastically off tone for the comic strip it came from. Generally a light hearted series and then BAM, have something that in context is utterly brutal.
Nowadays it's so divorced from it's context that it's essentially just a meme.