this post was submitted on 18 Feb 2026
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[–] Quibblekrust@thelemmy.club 3 points 21 hours ago

Strongly suggesting the placebo fooled their body into releasing it's own endogenous opiates.

I don't get it. Why would they assume that? You're given a placebo pain reliever and it relieves pain. Then you're given a nalaxone, which you, the patient, knows blocks opioids. In both cases, it could just be the placebo effect. You could be given water and told it's nalaxone, and it could have the same effect.

Were they not told they were being given nalaxone? Were there four cohorts? Were some of the people who got placebo painkillers also given placebo nalaxone where it didn't block the pain relief?

I can't read the paywalled article.