153
How about we play, "Never have I ever"?
(fedia.io)
you are viewing a single comment's thread
view the rest of the comments
view the rest of the comments
this post was submitted on 24 Sep 2024
153 points (92.3% liked)
Asklemmy
44149 readers
1439 users here now
A loosely moderated place to ask open-ended questions
If your post meets the following criteria, it's welcome here!
- Open-ended question
- Not offensive: at this point, we do not have the bandwidth to moderate overtly political discussions. Assume best intent and be excellent to each other.
- Not regarding using or support for Lemmy: context, see the list of support communities and tools for finding communities below
- Not ad nauseam inducing: please make sure it is a question that would be new to most members
- An actual topic of discussion
Looking for support?
Looking for a community?
- Lemmyverse: community search
- sub.rehab: maps old subreddits to fediverse options, marks official as such
- !lemmy411@lemmy.ca: a community for finding communities
~Icon~ ~by~ ~@Double_A@discuss.tchncs.de~
founded 5 years ago
MODERATORS
That’s why people smoke it. You can feel how high you are with each puff and can control it easily.
Weed may be strong, but it isn’t fentanyl. One toke over the line is not the danger zone—even less so than one alcohol shot over the line.
It's not for me. I don't know why, but it makes me loopy. With beer, your liver builds a tolerance to it over time and your mind learns to not say certain things when under the influence. With weed, that tolerance is 100% mental as far as I can fathom, and I'm just too weak-willed under its influence apparently.
The tolerance isn’t totally mental, it just takes longer to build and recede than alcohol does.
To each their own though, not trying to pressure anybody.
where does the tolerance come from though? With alcohol it's very clear that there's one organ doing the heavy lifting. With weed, I have no idea.
Of course! Likewise, I'm not trying to shame anyone for picking weed over beer. Each to their own
Edit: Apparently it's "CB1 receptor density" in your brain that handles the tolerance.
Indeed, a lot of drugs that are non toxic have tolerance created in the brain, while more toxic drugs have to get processed by the kidneys and liver, which is why the functioning of those organs contributes to tolerance.
It’s not your liver, it’s your GABA receptors downregulating that gives you a tolerance. Your liver helps with the duration and hangover but the lower peak intoxication is mediated by the receptors. Likewise with cannabis, your THC receptors downregulate to give you a weed tolerance. It is also processed by the liver.