104

Like Fluoride or Oxygen.

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[-] ThirdWorldOrder@lemm.ee 69 points 1 year ago

Just about anything including water or salt

[-] howrar@lemmy.ca 48 points 1 year ago

Not just about. Literally everything is lethal at a high enough concentration.

[-] fiat_lux@kbin.social 42 points 1 year ago* (last edited 1 year ago)

Panadol / Paracetamol / Tylenol / Acetaminophen / C8H9NO2 is exceptionally easy to overdose on. I've done it accidentally a couple of times. It causes liver damage at even lower overdoses, you really don't want that.

The maximum dosage is 1g every 4 to 6 hours, maximum total 4g a day. I am no doctor but I strongly recommend 6+ hours between doses (I set a timer) and I try very hard to not get to 3g or above per day. It's even worse that plenty of medications just throw it in to the mix casually.

Unfortunately as the only first line of defence I have against pain, I cannot avoid it altogether. Redflags for me were light abdominal pain and yellowing of skin under eyes. Plus fatigue, but that's normal in my world.

[-] ilex@lemmy.world 16 points 1 year ago

Huh. That might explain the last two weeks. Dental pains. Lot's of tylenol. And why I feel much better now.

[-] FaceButt9000@lemmy.world 12 points 1 year ago

For dental pain I recommend ibuprofen (advil). Seems to work significantly better than acetaminophen (Tylenol) and seems to be much safer.

[-] Dhs92@programming.dev 7 points 1 year ago

Some people can't take NSAIDs unfortunately

[-] ilex@lemmy.world 7 points 1 year ago

I was dual wielding.

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[-] Agent641@lemmy.world 36 points 1 year ago

Weed. A gram will get you high. A woolpack full of it can crush you like a grape if falling from the hay loft.

[-] ilex@lemmy.world 10 points 1 year ago
woolpack
From Middle English wolpak, wullepak, equivalent to wool +‎ pack. 
A bag of wool, traditionally weighing 240 pounds.

TIL, Thx

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[-] AsslessChaps@lemmynsfw.com 33 points 1 year ago

According to people I know, I’m only ok in small doses.

Then they leave.

[-] Hadriscus@lemm.ee 12 points 1 year ago

So you've never had so far the opportunity to test whether or not you are lethal at higher doses ?

[-] BilboBargains@lemmy.world 6 points 1 year ago

I think we have a volunteer

[-] Guy_Fieris_Hair@lemmy.world 32 points 1 year ago

Took a Hazmat class today and the big thing they drilled into our heads was "Everything is toxic at scale." So make anything you want and there is an IDLH concentration.

[-] bevan@kbin.social 28 points 1 year ago
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[-] FuglyDuck@lemmy.world 25 points 1 year ago

dying is a pretty big red flag, you ask me.

[-] fujiwood@lemmy.world 16 points 1 year ago

Okay. Do you think dying is a pretty big red flag?

[-] FuglyDuck@lemmy.world 13 points 1 year ago

I guess I did ask for that.

I also guess you like to tell dad jokes.

[-] keeb420@kbin.social 21 points 1 year ago

Botulism can kill you, botox can kill your wrinkles.

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[-] scarabic@lemmy.world 19 points 1 year ago

It’s been said a lot that light alcohol consumption is actually good for your health, but this is not actually true. It improves some health outcomes but the benefits are outweighed by the risk. There is no safe amount of alcohol consumption.

[-] BilboBargains@lemmy.world 17 points 1 year ago* (last edited 1 year ago)

Hilarious how the alcohol lobby scratched around for years looking for a good news story about alcohol and came back with some weak sauce link between red wine and heart disease. Meanwhile, 50% of reported sexual assaults are linked with alcohol. Probably more like 80%. How is alcohol legal and LSD is a schedule 1 substance? There is no lethal dose and has been discovered as a treatment for resistant depression and PTSD, OCD, etc. Our drug laws are completely wack.

[-] Corkyskog@sh.itjust.works 10 points 1 year ago* (last edited 1 year ago)

The real elephant in the room is alcohol is much more destructive and just as addictive than measurable controlled doses of opoids, and also equally if not more destructive than stimulants like amphetamines and cocaine. It's basically the worst drug in every metric. If every alcoholic got their drinks replaced with MS Contin and or weed, the strain on the health system would be much less. Not to mention all the other negative externalities related to alcohol intoxication.

I say all this as someone who drinks. I am going to ensure my child is aware of all the negatives at an early age and be open to discussion about substances. People either like or dislike alcohol, and the people who like it have no self control. It's a stupid drug, I wish I was never introduced the way I was.

Don't even get me started on the alcohol companies producing alcoholic mountain Dew, freeze pops and Sunny D... and they have the gall to ban flavored vapes haha.

[-] BilboBargains@lemmy.world 6 points 1 year ago

I have a feeling that alcohol will come to be viewed in a similar way we now look at religion. It's a cultural artefact from an ignorant time. It serves some purpose and there is a basic utility but overall it has a toxic effect. I hear that research is ongoing to find a credible alternative molecule without the deleterious health outcomes.

Western society has a generally incoherent and childish attitude to substances. Some are viewed as evil e.g. heroin but when this drug turns up in a therapeutic setting, it inexplicably becomes medicinal i.e. diacetylmorphine, which is the acceptable face of heroin, used for terminal cancer treatment.

No substance should be viewed as either panacea or disaster. They are tools that we can use when the time and place is appropriate. We ought to educate ourselves and have honest conversations. Prohibition is getting in the way of this effort and it must go. In it's place we install education, healthcare and hygiene for the mind.

Happy to find a fellow psychonaut. What's your next project in this area? I am considering a psychedelic voyage to the Netherlands.

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[-] MxM111@kbin.social 19 points 1 year ago

Everything is good in moderation. Even drinking too much water can lead to death.

[-] skillissuer@discuss.tchncs.de 18 points 1 year ago

ionizing radiation, according to some hypothesis, vitamin E, selenium, zinc,

there's no single "red flag" everything is different

[-] agitated_judge@sh.itjust.works 17 points 1 year ago

Everything. Literally everything can be fatal in large enough quantities. Quote from one of my chemistry professors: "there are no lethal substances, only lethal doses"

[-] clockwork_octopus@lemmy.world 9 points 1 year ago
[-] rich@feddit.uk 8 points 1 year ago

Remember the Wii craze in 2007? There was a radio competition called Hold Your Wee for a Wii in which the contestants had to drink throughout the day without going for a piss. One died.

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[-] Sethayy@sh.itjust.works 6 points 1 year ago

"The dose makes the poison" -some old dude that like found the pharmaceutical industry

[-] plactagonic@sopuli.xyz 16 points 1 year ago

There are lots of things that our body needs in really small doses. But anything above can be lethal.

Some things needs to be in really specific compounds. Like chrome we need really small dose of Cr3+ but Cr6+ is carcinogenic.

[-] Kolanaki@yiffit.net 15 points 1 year ago* (last edited 1 year ago)

Water. You need it to live, but you can also drown in it or even drink too much and dilute your blood and die.

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[-] Cheriebarie@reddthat.com 14 points 1 year ago

My medication. Lithium in small exactly precise doses according to each individual is helpful. But we have to take blood tests to check the toxicity.

We have to stay hydrated and be really careful if we are sick or vomiting

A warning signs is shaking (I tests my hands regularly), nausea and outcome is dying. Ha.

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[-] HiddenLayer5@lemmy.ml 14 points 1 year ago* (last edited 1 year ago)

Acetaminophen/Paracetamol. The safe therapeutic dose is very close to the toxic dose. While most people don't intentionally overdose, at least not for treating illness symptoms, the problem arises when they take multiple medications that all contain acetaminophen, following the label for all of them can easily net you a toxic dose.

Chubbyemu video: https://www.youtube.com/watch?v=VSqrCgFMsCI

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[-] Travalanche@lemmy.world 11 points 1 year ago

Cocaine. A red flag being your heart beating itself to death inside your chest.

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[-] Extrasvhx9he@lemmy.today 11 points 1 year ago* (last edited 1 year ago)

The human body is pretty weak so anything in high concentrations can probably kill us. It's no steel

[-] Chainweasel@lemmy.world 10 points 1 year ago
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[-] T156@lemmy.world 9 points 1 year ago

Heartbeats. 60 - 70 is good (you can get away with lower if you're fit, but anything below 40 is bad), and anything above 180 - 200+ tends to be quite bad for your health.

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[-] Drusas@kbin.social 8 points 1 year ago* (last edited 1 year ago)

Vitamin A. Probably others as well.

Also, water.

[-] JoBo@feddit.uk 7 points 1 year ago

Blood sugar. Vital that you have enough to continue functioning but if it stays too high for too long, it will disable and eventually kill you.

[-] 257m@lemmy.ml 7 points 1 year ago
[-] CaptainBlagbird@lemmy.world 6 points 1 year ago

What's the LD50 of the internet? 🤔

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this post was submitted on 28 Aug 2023
104 points (90.6% liked)

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