Don't take MDMA or cocaine while drinking, it's toxic and you will likely blackout, especially on the molly. Never take benzos while drinking, it's a waste of benzos and you will definitely black out and potentially even die.
Hallucinogens generally don't mix with alcohol, although some people claim LSD and a couple drinks go well together.
Cannabis will intensify your tipsiness when drinking. It is or used to be called being "cross-faded". If you are going to smoke cannabis and drink, smoke first as it will regulate how much alcohol you consume.
Lastly it's important to remember how alcohol works. The fun chemicals in your brain get produced as your BAC increases. To have the most fun, less negative side effects you stretch your alcohol out over your drinking period. So let's say you plan to have six drinks over 4 hours. You will enjoy the experience much more if you have two drinks for the first 3 hours, rather than taking 4 shots in the first hour and then two drinks after it. Once the BAC stops rising the fun stops and you are left with mostly negatives of dizziness, fogginess and possibly nausea.