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The headline (and the article for that matter) are very sensationalist and I don’t think they’ve presented this in a balanced way. They are discussing how sorbitol behaves in zebrafish with limited data presented on human biochemistry, and they discuss it in a vacuum without quantifying the amount of sorbitol it takes to cause a problem. Yes, any substance in excess can be harmful, but the amount of sorbitol in food compared to the amount of high fructose corn syrup makes it the substantially lesser evil. The artificial sweeteners are vastly more potent than actual sugar, so you don’t need very much of it to get the same amount of sweetness. High fructose corn syrup is used in massive amounts in food and is much worse for you on the scale that either substance would be consumed.

It’s sorbitol.

Phew! Thank God I'm not a zebra fish, otherwise I'd need to seriously reconsider my diet high on sorbitol.

Sorbitol-degrading Aeromonas bacterial strains convert the sugar alcohol into a harmless bacterial byproduct.

“However, if you don’t have the right bacteria, that’s when it becomes problematic. Because in those conditions, sorbitol doesn’t get degraded and as a result, it is passed on to the liver,” he said.

Pretty big caveat but the sensationalist headline is all people will see.

... In fish.

The article doesn't read as very concerning. Too much of anything usually means bad. Under the right conditions anything can be bad. Figuring out what can be bad and when it can be bad can often take decades. Don't stress too much on trying to optomize out anything that can do you harm in a diet. You'd have nothing left to eat and even the greatest collective of biologist getting together to make the greatest nutritional shake meal replacement would probably miss something that causes issues decades down the line or people drink too much and overdose

Give up sugar. Try it, and tell me it isn't addictive.

Give up all sweeteners, because keeping them just makes you crave more, making it much harder.

I gave up sugar, and most fruits except berries. It made staying at my ideal weight MUCH easier. I really don't need to think about it, I weigh myself every few weeks, and I'm always at my ideal weight. Exercise is the other part of the equation, I think we need to do both.

Tbh I am betting that it's gonna come out that they've known about the health risks all along, but they tried to ignore/cover it up for profit reasons.