this post was submitted on 24 Jul 2025
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Science

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[–] HowRu68@lemmy.world 40 points 1 month ago (2 children)

We should live in Shroom world, everybody will be connected by the mycelium, live long and prosper together.

[–] NaibofTabr@infosec.pub 20 points 1 month ago (6 children)

Yes... let the cordyceps eat your brain... become one with the omnifungi... let our will become yours... listen to the mold as it whispers in your mind...

[–] Mac@mander.xyz 9 points 1 month ago

🤷‍♂️

Okay, sure, why not

[–] Vanilla_PuddinFudge@infosec.pub 3 points 1 month ago

Eh, beats fascism.

[–] steal_your_face@lemmy.ml 2 points 1 month ago

I am the Globglogabgalab

[–] lb_o@lemmy.world 2 points 1 month ago

WE ARE THE ONE!

[–] otter@lemmy.dbzer0.com 1 points 1 month ago

Did you drop this? /s

You're making it sound pretty damn amazing, frankly. Have you looked around lately? 😅😶‍🌫️

[–] Mac@mander.xyz 0 points 1 month ago* (last edited 1 month ago)

edit: double post

[–] redchert@lemmygrad.ml 1 points 1 month ago

There is already fungi that grows in your throat. Humans are connected to the mycelium - the most advanced lifeform on this planet.

[–] jeffw@lemmy.world 29 points 1 month ago (1 children)

Forgive me for doubting any studies that don’t involve blinded trials… but this is just one study. Let’s see if it can be replicated before we get excited

[–] remotelove@lemmy.ca 14 points 1 month ago (1 children)

Oh, I am going to try to replicate this study. I'll hit you back in about 50 years if it worked.

[–] jeffw@lemmy.world 2 points 1 month ago (1 children)

It takes you 50 years to transform into a mouse?

[–] remotelove@lemmy.ca 1 points 1 month ago (1 children)

Or sooner, once the medicine kicks in.

[–] jeffw@lemmy.world 1 points 1 month ago

Whoa. You’re a mouse now?

[–] Laser@feddit.org 9 points 1 month ago

A newly published study in Nature Partner Journals’ Aging demonstrates that psilocin, a byproduct of consuming psilocybin, the active ingredient in psychedelic mushrooms,

Maybe my memory is wrong, but I had it the other way around: Psilocin is the active substance, but its not very stable. Psilocybin gets metabolized to Psilocin. Calling it a "byproduct" is kind of underselling it. Psilocybin itself isn't active by itself.

Quick wiki check confirms this. I always have troubles with articles opening with. I can't even read that as unfortunate wording.

[–] BodyBySisyphus@hexbear.net 9 points 1 month ago (1 children)

Results indicated that the mice that received an initial low dose of psilocybin of 5 mg/kg, followed by a monthly high dose of 15 mg/kg for 10 months, had a 30% increase in survival compared to mice who hadn’t received any.

So if we take a standard 80 kg adult male, 80 * 15 mg = 1.2 g, which sources indicate is enough for a standard trip. That's also like almost half an ounce of dried mushrooms. Time to start tripping... for science.

[–] HootinNHollerin@lemmy.dbzer0.com 5 points 1 month ago (1 children)
[–] BodyBySisyphus@hexbear.net 8 points 1 month ago (1 children)

Yeah, the paper is talking about pure Psilocybin. I double checked and the rule of thumb is around 1% psilocybin by dry weight so I was actually off and you'd need closer to three ounces.

[–] Castor_Troy@hexbear.net 4 points 1 month ago* (last edited 1 month ago) (1 children)

(15 mg psilocybin / 1 kg body weight) * 80 kg body weight = 1200 mg psilocybin

1200 mg psilocybin * (1 g psilocybin / 100 g dried mushrooms) = 12 g dried mushrooms

I think it's 12 grams dried mushrooms, which is almost half an ounce, like you first said.

[–] Maturin@hexbear.net 7 points 1 month ago (2 children)

Shouldn’t it be 1200 mg / 0.01 = 120 g of dried mushrooms?

[–] Castor_Troy@hexbear.net 2 points 1 month ago

(15 mg psilocybin / 1 kg body weight) * 80 kg body weight = 1200 mg psilocybin

1200 mg psilocybin = 1.2 g psilocybin * (100 g dried mushrooms / 1 g psilocybin) = 120 g dried mushrooms

There we go.

[–] Castor_Troy@hexbear.net 2 points 1 month ago (1 children)

Thank you. I was staring at it and knew the units weren't canceling out. That's an insane dose though.

[–] Maturin@hexbear.net 4 points 1 month ago (1 children)

Even the “low dose” is the equivalent of almost 2 oz per dose. Those mice got to convene with the mice gods on the reg I’m sure.

[–] propter_hog@hexbear.net 4 points 1 month ago

Boofing a whole tray of penis envy shrooms... for science

[–] sixtoe@lemmy.blahaj.zone 8 points 1 month ago

HOLY SHIT IM GONNA LIVE FOREVER

[–] wideopenarms@hexbear.net 3 points 1 month ago* (last edited 1 month ago) (2 children)

Idc, I'll just die old, no one's ever gonna get me to willingly take hallucinogens

Go ahead and hit me with the downbear, don't care if that's an L take or not

[–] otter@lemmy.dbzer0.com 2 points 1 month ago

You do you. Have fun!

[–] isolatedscotch@discuss.tchncs.de 0 points 1 month ago (1 children)

no healthy adult should feel the need to take any drug

[–] Rivalarrival@lemmy.today 0 points 1 month ago

Need? Of course not. Desire? Certainly.

[–] Hirom@beehaw.org 1 points 1 month ago

Wake me up when once there are results of a well-designed clinical trial.

My understanding of the article is they're extrapolating from experiments on mice and on a few human cells in a lab.

[–] Bronzebeard@lemmy.zip 1 points 1 month ago

Nuh uh. I've seen the Last of US. We all know where this ends up