Hades?

Sorta

Age of Mythology, and Titan Quest 1+2 (spinoff by same devs). There's a DS tactical spinoff of Age of Empires that's not very good but worth trying. Torchlight might be similar to Titan Quest.

I've also been playing Saiyuki: Journey West (PS1) which is based on Buddhist/Hindu mythology. 'Journey to the West' also inspired Wu Kong, 'Enslaved: Odyssey to the West', and Dragon Ball series.

God of War (Greek n Norse), Darksiders (Christianity), Immortals: Fenyx Rising (Greek), Hades (Greek), Hellblade: Senua (Norse), Okami (Japanese), Folklore (Irish), Dante's Inferno (Christianity). You're not really 'playing as' myths but mostly fighting them in these series.

Since it hasn't been mentioned, Okami. You play as Amaterasu, the Japanese sun god

Age of Mythology. It's an RTS game from maybe 20 years ago, although there's a remastered edition that's less than a year old. I played the original version and the story and gameplay are both really fun. The controls definitely feel dated and clunky to me now though. I've not played the new version but I expect it's good too.

Specifically, you can play as Norse, Egyptians and Greeks with three main gods and nine(?) minor gods from each pantheon. You build up your civilization / town over several ages, managing your resource gathering and armies. Each age unlocks a new god with a new god power. Each god also has different mythical monsters that you can create such as jackals, hydras, wolves, etc. The original also had Chinese and Atlantians (Greek titans) as DLC, I don't know if they exist in the new version

Sakuna, of Rice and Ruins is about a goddess in a fictional but very shinto-adjacent religion in a country not quite, but not entirely unlike Japan. She's the daughter of her pantheon's God of War and Goddess of Harvests. She bashes monster heads and she sows rice, and both are important.

Fun and light-hearted, with a small cast of quirky likeable characters.

There is Fight of Gods, a mediocre 1v1 fighting game (in the style of Street Fighter). Has a few pretty cool music.

Athena's Track: Listen on YouTube https://youtu.be/lj6hfceo-3c or through Invidious https://inv.nadeko.net/watch?v=lj6hfceo-3c

I guess Oreshika: Tainted Bloodlines would count. It's a turn-based JRPG for Vita, don't know if there was any other releases. Your job is to manage a cursed Japanese clan where everyone lives for around two years, yet for some reason is able to reproduce with the help of Japanese gods. The pantheon is quite large, each god has certain elemental affinities and other interesting inheritable features.

Spartan: Total Warrior from the PS2 & Gamecube was I think an underrated or missed gem.

You don't exactly play as a lot of mythological things, but it tells a great story with action combat around a lot of really cool mythology. Some of the bosses were incredibly cool.

puzzle and dragons as a mobile game revolves around that idea for its non collab content.