I'm pretty sure it mainly comes down to either youth or hydration or a combination of both. I remember getting absolutely hammered in my 20's and having the worst hangover so far, but I had been drinking with the explicit purpose of getting fucked the hell up. Still went into work and found ice water and beef jerky to be my go to that day. Gatorade, water, and fattier protein foods would've also been a life saver imo. So either they're well hydrated and didn't know it or they simply haven't drank enough jäger, bacardi 151, everclear, and fireball yet...

[–] hector@lemmy.today 4 points 1 day ago

Hyrdration, and youth, play a big role, but it's more than that. There are subtances in the alcohol that also contributes to hangovers. Like byproducts of their fermenting, and I think they vary by what you are drinking.

[–] queermunist@lemmy.ml 4 points 1 day ago (1 children)

Hydration isn't actually the biggest factor. When you drink, your liver metabolizes alcohol into acetaldehyde, which is toxic. Hydration helps simply because being more hydrated makes poisons more tolerable, but dehydration isn't the cause of a hangover.

[–] Commiechameleon@hexbear.net 1 points 1 day ago (1 children)

Ah, as I'm reading the thread it seems to be the loss of b vitamins and magnesium as well. And while I can agree to a degree about the role of hydration not being the biggest factor, I've yet to get one while drinking and properly hydrating. I'll add the vitamins to the list of things to do when I decide to get hammered, but it's gonna probably take a back seat to taking a good 'ol blunt to the face debord-tired

However, I'd love to know how to rid the body of acetaldehyde? I'm assuming piss more?

[–] queermunist@lemmy.ml 2 points 1 day ago

It's metabolized in the liver, and oxidizes into acetic acid which is then bound to an enzyme (which is synthesized from vitamin B~5~, so that's where the depletion comes in) and further used to metabolize carbs and fats. Drinking water does... something? We're at the limits of my popsci knowledge at this point lol