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How about we play, "Never have I ever"?
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Why? I've just never been interested on altering my mood or perceptions using an external source. I don't even like the effects of alcohol.
I think it's so cool to see what happens to your brain with the effects of various chemicals. We're so convinced of our own sanctity, and feeling the world differently just disavows you of that in a few minutes.
I think LSD should be a common coming of age right. We'd all be better off, and better for each other, if we could realize we're each just a tiny blip in the world.
From what I've learned about LSD and psilocybin in popular science they do sound like effective tools for depression, PTSD and enhancing creativity. I don't have the means or the will to try and get it or experiment with illegal substances. I think therapies should definitely be developed around their application though. A coming of age right would also be very interesting.