DIY HRT

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Welcome!

This community exists for trans people and others to give each other advice and support regarding HRT.

Keep in mind that none of us are doctors. Read up on how to do things properly and double check any advice you are given.

Rules

Follow the instance rules.
Be accurate.
Don't make others worry unnecessarily.
Sources are appreciated.

Quick Facts

Different routes (oral vs injections vs trans-dermal etc) have the same results. Pick whichever option you are most comfortable with.
If you're doing feminizing hrt your boobs will randomly grow in bursts. Chest pain going away is perfectly normal.
It's unreliable to estimate your hormone levels based on signs. Take blood tests if they are available to you.
Remember to eat well, get enough sleep, and exercise! This will help you grow properly and look more masculine on testosterone or more feminine on estradiol.

Check out the pinned posts! They contain lots of useful links and resources.

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Dosage calculation for estradiol enanthate monotherapy (lemmy.world)

submitted 2 months ago by Berengaria_of_Navarre@lemmy.world to c/diyhrt@lemmy.blahaj.zone

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The recommended dosages I'm seeing vary quite a lot. How dependent is dose on, for example. I was planning on a 8mg loading dose followed by weekly injections of 5 mg to start but my supplier recommends 7.5mg per week which seems high.

I'm on the larger side so I'd probably need a slightly higher dose, but does anyone know a website where I can get pharmacokinetic calculations and the like? It seems like weight and body fat percentage would have an effect on dose but I haven't seen information on that.

I don't mind taking a higher dose, but I'd like to make it last if possible.

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[–] will_steal_your_username@lemmy.blahaj.zone 2 points 2 months ago

4mg-5mg weekly is very standard, but some do need a bit more to properly suppress T. 7.5 sounds like a way too high number for no real reason. Some people may need that, but the vast majority won't. I recommend sticking to your plan of 5 (or even reducing to 4) and then adjusting depending on what your blood tests show.

[–] Shirow@lemmy.zip 1 points 2 months ago* (last edited 2 months ago) (1 children)

I might be wrong, but your first guess was to me the best approach.

As far as I know, from a french trans national association. weight and body fat pourcentage doesn't play a role.

I use 5mg / week and I'm around 200pg/ml for estradiol. (Which is supposed to be between 100-200 if I'm right)

Testosterone ~1nmol/L (or 29ng/DL) I think my testosterone could be lower (I think it's supposed to go down to 0.5nmol/L), but the estradiol is where it's supposed to be for me. So I can go slightly higher to see if it suppress more T ( but I shouldn't go too high on E too.)

You mileage may vary of course. Please folks correct me if I'm wrong. I don't want to give false information.

Weight

Tap for spoiler

Oh, I'm still obese if that helps for the doubt about the weight. 108 kg ( from 125kg 5 month ago to give you context)

[–] Berengaria_of_Navarre@lemmy.world 1 points 2 months ago

Thanks