this post was submitted on 04 Apr 2026
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DIY HRT

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The recommended dosages I'm seeing vary quite a lot. How dependent is dose on, for example. I was planning on a 8mg loading dose followed by weekly injections of 5 mg to start but my supplier recommends 7.5mg per week which seems high.

I'm on the larger side so I'd probably need a slightly higher dose, but does anyone know a website where I can get pharmacokinetic calculations and the like? It seems like weight and body fat percentage would have an effect on dose but I haven't seen information on that.

I don't mind taking a higher dose, but I'd like to make it last if possible.

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4mg-5mg weekly is very standard, but some do need a bit more to properly suppress T. 7.5 sounds like a way too high number for no real reason. Some people may need that, but the vast majority won't. I recommend sticking to your plan of 5 (or even reducing to 4) and then adjusting depending on what your blood tests show.