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Dr. Matthew Phillips is a neurologist and Director of Neurology at Waikato Hospital in New Zealand. His emphasis is on applying metabolic strategies in healthcare to heal many difficult disorders at their core through fasting and ketogenic diets. https://www.metabolicneurologist.com/papers

A fascinating discussion about designing research protocols for mitocondrial metabolic research with cancer patients, alzheimer's patients, als, parkinsons, etc. A really illuminating walk behind the curtain.

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How Ketosis Can Improve Brain Health - Dr. Mathew Phillips Shares the Science

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Dr. Matthew Phillips discusses how ketosis can enhance brain health, particularly regarding neurological conditions such as Alzheimer's, Parkinson's, and brain cancers. He shares insights into the metabolic therapies he utilizes, primarily focusing on fasting protocols and ketogenic diets. His research indicates promising results, particularly in improving non-motor symptoms in Parkinson's disease and quality of life in Alzheimer's patients. Phillips emphasizes the importance of metabolic health and its broader implications for tackling various lifestyle disorders.

Key Points

Introduction to Dr. Matthew Phillips

Dr. Phillips is a neurologist with a focus on applying metabolic strategies to treat various neurological diseases, including neurodegenerative disorders and brain cancer. He emphasizes the need for nutritional and dietary changes as part of treatment.

The role of ketosis in brain health

Phillips discusses how ketosis, induced through ketogenic diets and fasting, can provide therapeutic benefits for neurological patients, improving symptoms and potentially enhancing brain health.

Metabolic therapy for Parkinson's disease

Research highlights that a ketogenic diet significantly improves non-motor symptoms of Parkinson's by 40%. This contrasts with only 10% improvement seen in patients following a standard low-fat diet.

Alzheimer's disease study insights

While a ketogenic diet showed promise in improving the quality of life for Alzheimer's patients, the cognitive improvements did not reach statistical significance. Nonetheless, the functional aspects of life improved substantially.

Challenges in conducting research

Dr. Phillips has navigated challenges in setting up clinical trials for brain cancer treatment protocols, focusing on the integration of fasting and ketogenic diets alongside conventional therapies.

Importance of metabolic health

Emphasizing that intermittent fasting can be a foundational lifestyle change to combat various metabolic disorders, Dr. Phillips advocates for fostering metabolic health early to prevent the onset of neurodegenerative diseases.

Community and support for metabolic therapy

Phillips stresses the need for community support and proper guidance for patients undergoing metabolic therapies, as this can significantly influence adherence and outcomes.

Future of metabolic therapies in neurology

The talk underscores the potential for further research into metabolic therapies for complex conditions like ALS and Huntington's disease, emphasizing the need for more clinical trials to validate these approaches.

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[–] jet@hackertalks.com 1 points 7 months ago* (last edited 1 month ago)

During this talk they discuss previous research protocols, current protocols, and possible future protocols.

There is lots of promising avenues of further research around mitocondrial function. Near the end of the interview it's mentioned that you could view metabolic syndrome moderate stage mitocondrial disfunction, and cancer/alzhimer's/parkinsons as advanced mitocondrial disfunction - I've never thought of it that way, its a very compelling model..