I actually have some opinions on the Plus Patch. I want to phrase this really carefully as Wesp5 is a hero for his work and dedication through the years, but he started taking a lot of liberties the last maybe 5-7 years, and the Plus Patch now contains stuff that is more mod than patch/restoration.

It has gotten to the point where I wish there were 3 tiers of unofficial patch, not two. The vanilla patch is only bugfixes, and lots of the stuff added back in the Plus Patch was actually good but just missing due to poor code or not being completely finished but 90% there. I wish there was a patch with just the bugfixes and those most obvious content restorations.

In the Plus Patch as it exists today, though, you have a lot of stuff that was cut for a reason shoehorned in, like unused OST tracks Wesp5 has inserted according to personal taste, or areas (and a quest) that were barely started where he himself filled in the blanks. And even complete mod content that - while they could be argued to be improvements - are alterations to the game according to Wesp5's vision.

You still need the basic patch to even run the game, of course, otherwise it's literally unplayable. But these days I recommend the Plus Patch for a second playthrough. Playing as Malkavian is a good enough reason for a second playthrough, anyway.