Yep! If you know you'll have a bare bed, the sleeping bag can be used as bedding so you can save packing a blanket. If you know you'll be in decent motels or better, you can save on packing the bedding if it's not specialized. The only specialized thing I need for road trips are road atlases. Make sure you know how to read a map before you need it though. I assume this is for the eclipse, so make sure to pack bug spray and a thick sweatshirt if you're coming to the Midwest