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Trump may be mystery patient in odd case of 79yo getting experimental obesity drug
(arstechnica.com)
this post was submitted on 23 Jun 2026
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Question for someone who knows more about GLP-1 drugs than myself - if you're taking the drug regularly, and you're also self-administering a medicinal Whopper and large fries >1x per day, will you still lose weight? The stuff works but thermodynamics still applies?
The class of drugs works by suppressing appetite. So you just eat less and feel good about it. Which makes restaurant chains very, very nervous.
They should just charge more for less amount of tastier food.
Personally I'm not a fan of the thought of eating testes. There are markets for it, but do you think this has the required mass market appeal to save the chains?
Haha typo
Been on a GLP-1/GIP compounded injection for a year. Lost 90lbs.
I physically have a hard time overeating on fats/protiens. Like I want to vomit. Meat consumption is way down from before.
Simple carbs like starches and sugar I can overinduldge on but seem to get sick faster than before taking the medication.
It mostly helps with food related cravings but its not a silver bullet. I can still fallback to emotional eating under high stress and fluctuate +5 lbs with water retention. Its just much easier to recover.
I lost about 1/3 the weight on my own tracking everything. With the medication it tripled the rate of loss and I didn't need to track anymore. I'm much more able to trust my body and hunger signals developing a healthier relationship with food.
Meds kill hunger. You just feel full quickly and for a long time. My coworker brings a normal portion of food to work and only eats maybe half. They told me they don't really feel hungry, but know they have to eat. They eat once a day. I'm pretty sure its just anorexia in a shot. Also this helps with physical hunger, so, if you emotional or stress eat, it won't help as much/lose weight as quickly.
Thanks for the info! So it just makes you feel full, but wont neccesarily help with an eating disorder.
It can actually help with eating disorders in that apart from making you feel full sooner, it also seems to have a reduction in addictive behaviours of all sorts. There's talk of research being done for things as diverse as opiate addiction and ADHD - where improved executive function might look very like more will-power/thinking time around impulsive behaviours.
Have ADHD. I've been taking a GLP-1/GIP compounded injection for a year and it has done nothing for nicotine or poor impulse control shopping. If anything it made the shopping worse as clothes no longer fitting becomes a great excuse to shop. At least that's my experience.
I would love an ADHD medication that had no effect on my hunger. I eat normally when unmedicated (but everything else falls apart), but every medication either makes me voracious or slightly nauseated at the idea of food.
Probably a silly question, but have you asked your doctor if you could combine or cycle medications that push your appetite up and down so they balance out?
That’s kind of what I do- vyvanse works best for me, and when my doctor gets too worried about my weight, she’ll switch me to strattera for a month or two- but I do worry about essentially having a yearly hibernation cycle with body fat.
Have you tried non-stimulating adhd meds? Other than terrible heartburn during the tritation period (meaning, it's gone by now), I've had no change in gut feel
Yeah, those are actually also fine for my hunger, but even after 4-6 weeks of use, they make me need to sleep about 15 hours a day. While taking stimulants, I only want to sleep like that on the day of the first missed dose. After the third day, I’ve got a basically normal sleep schedule (at least normal for someone with ADHD missing medication), so it’s not withdrawal from stimulants that causes it.
probably also suppressing his cocaine and adderal addiction too.