Honestly I dunno. From the grower/biology difference there's a difference in growth and cold climate resistances which is why almost everything is some indica hybrid.

From a smoker perspective it'd hard to say. I managed to score a pure sativa strain this month was super excited for it! The high ain't that much different tbh but maybe if I had a heavy indica strain I could actively compare minute differences. I believe the line between energized and slumped is more to do with overall bud quality and how much you intake + tolerance. A few too many hits turns me from energetic and relaxed to lethargic and spaced out. Terp profile and thca content has a big impact limoline really jives with me.