I have felt before like "nothing's going right and nothing is ever going to go right" as you seem to be.

Only the first half of that feeling might be true and the second is definitely untrue. It's not going to be perfect either, but it will be a mix of nice things, amazing things, annoying things and awful things.

If something is not working, try something else. That "something else" may be another method to get it work, or it may just be replacing your original goal with a different one.

Either way, success will come to you, as long as you take care of yourself and keep in good health, are open to broaden your definition of success and not focus on a singular objective that everything must go perfectly as planned. You've made it this far in life, that is a success in itself and I know you are capable of much more when you set your mind to it.

There are lot of things you can give up, the main thing is not to give up on yourself. Take breaks as you need. Start by fixing even the tiniest thing that needs fixing in your life, like picking up one sock off the floor, or wiping down your bathroom sink. Instead of thinking you've lost everything, start from what you have and build from there.

Even in the best of times, there's been news that has brought despair to me. The way to overcome it is to tune it out a bit, with music, with fresh air, or if it's a chronic problem, with therapy and treatment based on a physician's recommendation, and reframe your focus to things you can accomplish, have accomplished and will accomplish.