I'd argue that the power dynamic is the other way, but the more important fact is that "Manifest Destiny" and all the other genocidal tendencies of the west cannot be untangled.

Zionism is the expression of "Manifest Destiny" (and "Rule Britannia" and other European imperialism) in west Asia; it is part of their larger system of global imperialism, genocide, and destabilization. The US and the collective west does not have "some interest" in keeping the region destabilized- it has its entire interest there (while also having its interest simultaneously elsewhere), because it is pursuing global domination and hegemony, a hegemony that will only ever be secure if they were to genocide off or enslave and cull much of the entire rest of the planet. The US (and the collective west, all of which also is banking on the Eurocentric/Atlanticist system of genocide and imperialism remaining) cannot hope to maintain global hegemony if west Asia- the crossroads between Africa and east and west Eurasia- falls out of its grasp. They also cannot hope to maintain global hegemony if the Pacific does, or Latin America does, or the natural resources of Africa does, etc- or if large nations like China, Russia, India, and the rest of BRICS are allowed to develop such that their peoples have the same means, the same dignity and opportunities as the west- well, you get the gist. They require dominance (and that dominance can only be secured through mass destruction/genocide) and destabilization across the entire globe, or their free ride off the rest of humanity's backs is over.

American Manifest Destiny may have had its differences with Zionism in the early days- and it had its differences with Nazi Lebensraum, and Rule Britannia, Francafrique, and the Spanish/Portuguese empires and their worldview of the "treaty of Tordesillas" dividing the world between the respective nations- but eventually, they all coalesced together (with the US championing and marshalling the western nations in trying to maintain their dominance over the majority of humanity).