Good try, PDA is 1 in 2000 but VSD even more common. Both are failures to 'finish patching up' as you put it. Good analogy!
Both Ventricular Septal Defect (VSD) and Patent Ductus Arteriosus (PDA) involve structures in the heart that fail to close as they should. However, they differ in terms of location and function: Patent Ductus Arteriosus (PDA): This is a blood vessel that connects the pulmonary artery to the aorta in a fetus. It normally closes shortly after birth. Ventricular Septal Defect (VSD): This involves a hole in the septum, the wall that divides the left and right ventricles of the heart. Normally, this wall is completely closed.
Is this referring to the clinical trial into a new Alzheimer's drug, Donanemab? (Kisunla brand name)