[-] Apicnic@lemmy.blahaj.zone 3 points 11 months ago

To me it's the best value for price bourbon I've found, and it's very good. I haven't tried very many of their higher end or limited offerings though.

[-] Apicnic@lemmy.blahaj.zone 5 points 11 months ago

I recently had to build out my business casual wardrobe as well. Madewell has taken so much of my money for both regular clothes and business ones. Decent deals on sale and generally a great quality. I'm also tall, and they tend to offer a tall version of everything which is so lovely.

Zara on sale had some decent deals of meh quality stuff, and I did some last bit of filling out with h&m stuff since the clothes budget was blown. H&m has some stuff that will look good for a bit, but long-term quality isn't great.

[-] Apicnic@lemmy.blahaj.zone 3 points 11 months ago

Go fiddle with the calculator on the website I linked to see how injecgion time changes peak-trough gap in the hormone curves. But generally I want stable levels because research shows we need a minimum amount of estrogen in order to have feminizing effects. We don't want to overshoot it because your body will create SHBG at too high of levels. I've never seen any research that hints at varying levels be more effective.

[-] Apicnic@lemmy.blahaj.zone 5 points 11 months ago* (last edited 11 months ago)

I really don't know why some of the more conservative dosing recommendations still give two week dosing schedules for EV. It has a lower half life than cypionate and should be injected more often, assuming you're aiming for stable levels (most people are). A lot of our original recommendations for transfem people were based around studies for populations with prostate cancer and menopause, and it seems like dosing strategies for them have stuck around.

I personally wouldnt ever go over a week long dosing of ev, and would likely switch to twice weekly injections if were I on it. The people over at transfemscience.org put together a neat way to visualize the difference in esters for achieving a steady state dose based on the pharmacokinetics of them all. Basically, at this point if I get a recommendation from a doctor for 14 day dosing of EV, I'm going to assume they're not up to date on current feminizing hrt research and are likely going to also be giving old information about things like IM vs SubQ injections.

Finally, nobody should ever be paywalled from medical information (and it's pretty abhorrent that this research even has to have hoops to jump around to get through). Just as an fyi for anybody else reading this, most articles that aren't brand newwill have a copy of it you can access by its doi number on sci-hub.ru (or another mirrored domain, searching scihub normally gives a list of current working addresses). In the case where it isn't available yet, the journal should provide a way to email them asking for specific articles for patient access.

[-] Apicnic@lemmy.blahaj.zone 4 points 1 year ago

...it's definitely real words, at least I though. Did you get a non English torrent or something? Or do you not ever hear southern accents?

[-] Apicnic@lemmy.blahaj.zone 11 points 1 year ago

In general, body hair will reduce slightly on hrt. It's still there, but in particular I saw a lot less growth for chest hair. If laser works for your skin/hair color combos at a practioner near you, I found it very effective and tolerable. Otherwise I use a safety razor for everything else. Once you're good with it, it's a very close and low irritation save.

For facial hair, almost everybody will see no effect with hrt. New growth (as in fully new follicles) should stop, but any existing hair will need to be removed if you want a smooth face all the time. I did laser for some initial clearing and now am doing electrolysis to finish up.

[-] Apicnic@lemmy.blahaj.zone 9 points 1 year ago* (last edited 1 year ago)

A note for everyone who is interested in injections but doesn't like IM, you can also do subcutaneous injections. My understanding is that estradiol in common preparations is a depot injection where absorption is controlled less by physical factors and more from the lipophilicity of the medicine itself.

Anybody who's interested can look for the article "Comparison of the Subcutaneous and Intramuscular Estradiol Regimens as Part of Gender-Affirming Hormone Therapy" published out of Dr. nippoldts group at Mayo recently.

[-] Apicnic@lemmy.blahaj.zone 5 points 1 year ago

Anybody dislike the production today even if the race has a great end? It felt like it took so long to see replays of any significant incidents/moves, if we saw them at all.

Plus, it was great to watch the four racing at the end for so long, but why take away the time splits? They just showed like lap times between two drivers at a time for all of it.

[-] Apicnic@lemmy.blahaj.zone 3 points 1 year ago

I feel like hair volume and fun styles, plus a lot of late 90s early 00s clothing is coming back in style right now! I'm having fun wearing it this time around.

[-] Apicnic@lemmy.blahaj.zone 6 points 1 year ago

I've tried to use different types of corn flour, but it's never quite right. The nixtamilization process dramatically changes the texture of the resulting masa. Fresh masa is even better, and can be made yourself if you're up for a project day.

I agree that flour tortillas may be your best bet if you can't find maseca. A wine or round liquor bottle with the label removed makes a great impromptu rolling pin.

[-] Apicnic@lemmy.blahaj.zone 102 points 1 year ago

The majority of my friends leaving Austin have done so because of state politics. It's hard to feel safe when you're queer in Texas.

[-] Apicnic@lemmy.blahaj.zone 5 points 1 year ago

Maybe this is the rumored aero stall when drs is on? It seems like there's still some massive aero efficiency differences when the flap opens.

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Apicnic

joined 1 year ago