I disagree with your assessment of cocaine. It tends to make me awake, calm, and talkative—not really bipolar. The comedown can include a little anxiety, but it isn’t that bad—mostly just still feeling wake when you are out of happy chemicals from the high.
If I were to try to make a similar generalization, I would say:
[Cocaine Wakefulness Unit] is equal and opposite to [Marijuana Sleepiness Unit].