This opener will work in essentially all situations. There are technically ways to get slightly more potency by doing some cursed things and using a different opener each minute, but those strats are just theoretical and any movement or fight mechanics would disrupt them. Other things to consider would be Swiftcasted Wild Rage in the opener instead of Winged Reprobation if you're doing a fight where you would have Wild Rage for Revenge Blasting or something.