General advice is smart switches, dumb bulbs. Switches mean that you can control the light without getting out your phone, or whatever it is you use to control the bulb. Sure HA can talk to many bulbs, but only if the switch is on. Guests will not have the ability to control your bulbs - either there is too much work to install an app for a short stay, or the system is a security nightmare (often both). Use a smart switch because they have a control on the wall that guests can use to get what they want done without having to worry about apps.
Most often you can choose bulbs with the right color temperature, but if not some dimable bulbs change color temperature. If this is not good enough two lights: a general room like, and a separate special effects light, don't combine them (HA can control both, but they are separate systems generally not used at the same time)