this post was submitted on 31 Dec 2025
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[–] mrmhm@lemmy.world 20 points 19 hours ago
[–] RobotToaster@mander.xyz 28 points 21 hours ago* (last edited 21 hours ago)

From the actual study[0]

Human cerebral microvascular endothelial cells (hCMECs) were cultured and treated with 6 mM erythritol, equivalent to a typical amount of erythritol (30 g) in an artificially sweetened beverage, for 3 h.

Am I reading this right? They basically soaked brain cells in diet soda for three hours?

[0] https://journals.physiology.org/doi/full/10.1152/japplphysiol.00276.2025

[–] ExtremeDullard@piefed.social 27 points 21 hours ago (1 children)

I was expecting yet another aspartame-bashing article, but it's an erythritol-bashing one this time.

Look, it's really simple: all those sweeteners have been in widespread use for a long time. Wanna know if they're harmful? Do some stats correlating release dates in several countries and occurrence of this-or-that disease and death records. If you can't find a statistically-significant correlation, well... it doesn't prove the stuff is harmless, but chances are it is.

That's assuming there aren't already a kajillion inconclusive studies on the particular molecule you're interested in, as with aspartame.

[–] Slotos@feddit.nl 24 points 19 hours ago (1 children)

Compare it to sugar while at it. It doesn’t need to be harmless, it needs to be less harmful than sugar.

And that’s a fairly low bar to cross.

[–] ExtremeDullard@piefed.social 5 points 18 hours ago* (last edited 15 hours ago)

Sugar is like water and air: it's fine in reasonable quantities 🙂

As the saying goes, the dose makes the poison.

And the same goes for all sweeteners too. In fact, I know for a fact that consuming aspartame in large quantities is harmful, because I used to consume entirely too much of it every day by mistake, and I very much felt the effects when I quit.

[–] scytale@piefed.zip 4 points 15 hours ago (1 children)

Regardless of the methodology used for this study, I’ve switched to pure stevia now. I hate that a lot of stevia products actually use erythritol and just list it in small font.

[–] Ludicrous0251@piefed.zip 2 points 14 hours ago (1 children)

I've been swapping half of my sugar in my morning coffee with a few drops pure liquid monk fruit. No idea if that's better or worse than erythritol.

[–] scytale@piefed.zip 2 points 14 hours ago (1 children)

I’m not sure either, but I figured if it comes naturally from a plant, it might be safer.

[–] Ludicrous0251@piefed.zip 3 points 14 hours ago

Agreed, but then again, so does arsenic.....

[–] irishPotato@sh.itjust.works 21 points 22 hours ago (1 children)

“…The researchers did not yet test this in people. They went straight to the cells that line your brain’s blood vessels…”

[–] HairyHarry@lemmy.world 13 points 22 hours ago (1 children)

I don't remember giving them consent.

Is this not your signature on a magazine subscription from 1998? Always read the fine print.

[–] etherphon@lemmy.world 4 points 15 hours ago

Whatever it does, it makes me feel like shit, so I avoid it.