https://en.m.wikipedia.org/wiki/Anomie
Disappointed this wasn't mentioned in the article. Sociologists identified the problems of industrial urbanization and the destruction of "the town square" so to speak, socially, long ago. Emile Durkheim coined the word "anomie" in the 1890s when studying suicide precipitated by its increasing frequency as industrialization and urbanization are underway; both part of destruction of different structures under which humans evolved to succeed in; being part of a tribe and making a difference in ones work.
It's a funny point to mention as an atheist, but religion--with a massive asterix for pain, suffering, trauma and death--was one of the pieces that continued through urbanization to tie groups of people together in an understanding and worldview(again massive asterix on the consequences of organized religion) which helped give people a "tribe" in recent millenia. The relatively rapid decline of importance and power of religion in western societies in the last 100 years removed one of these key pieces that people used to understand the world around them and identify with it--for better or worse.
There is a reason undeveloped countries like Haiti--despite being the poorest nation in the western hemisphere--has much happier humans than "richer" ones; they still speak to one another, get to see their families and friends, know those in their "village" around them and who does what and where and why and their work's point and product is generally in their hands, e.g. palpable (manual labor, cooking, etc.). On the whole, these things make people happier than not--obvious exceptions notwithstanding.
Technology is just the latest acceleration of the anomie process, when, nearly complete with the process of ripping up human connection to each other and our work. Technology's implementation in the US, like most things in this country is implemented how best to serve the wealthy and powerful of capital and it's lobbyists with no caution or wisdom allowed, so no surprise to see new and horrible inroads into the continuing process of anomie as described by Durkheim almost 150 years ago.