I watched a quick trailer for Workers and Resources and the part focusing on a bus driving made me think of a head-in-the-clouds fantasy cool thing:

a city builder game. Click on a truck driving through to switch to a driving sim (think American/Euro Truck Simulator), on a train to a train sim, on a bus to a bus sim… Click on a person walking on the street and you get a The Sims-like interface and get the ability to switch into that game mode. And even though this is probably highly unrealistic and already too much, so why am I even thinking about scope, you could limit scope by locking to just this one city. Any vehicle routes out of the city have the vehicle disappear when you get to the city border. Sims already limited itself to one town/city, do that the same way.

After reading a few reviews for W&R apparently it scratches both a Transport Tycoon-type itch and regular city builder itches, so sort of like my above idea—a few games in one. Apparently it can be micromanagey, which appeals to me when I'm in a certain kind of mood.