I think Scotland will be the first to achieve independence from England since a good amount of people are starting to get sick of parliament. The UK used an obsolete law that's never been enforced just to make life harder for trans people and that's kind of been a big catalyst in Scottish independence gaining traction again. I don't think Northern Ireland will last much longer in the UK after that. The inevitable abolition of the monarchy will put an end to the UK since we wouldn't even be a Kingdom anymore. Either way this is definitely the end of the United KIngdom now and it's going to happen within the century.