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this post was submitted on 01 Jan 0001
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I personally try to steer clear of diphenhydramine for anything other than one off purposes just due to the research coming out regarding anticholinergics and possible cognitive decline. It sounds like you’re taking it relatively infrequently, so I’d guess that’s ok. Just linking here for others for visibility as it seems like perhaps not the best long term solution.
https://www.health.harvard.edu/blog/common-anticholinergic-drugs-like-benadryl-linked-increased-dementia-risk-201501287667
It’s very occasional use for me. I had friends (more like friends of friends) that were deep into recreational Benadryl abuse back in the 90s.
From my understanding it’s a low quality high…
…but they were low quality people.
I didn’t read the whole study, but I wouldn’t be surprised if they’ve completely forgotten who they are now and they’d only be in their 40s.