if you know how much you lose to static

That's the trouble, it didn't get vaporized or vanish. It's still in the grinder, or sticking to the collection bin. I'm not an expert or anything but I suspect that the residue oxidizing and mixing with the next batch will have more flavor impact than being a little off with your measurement.

Honestly, is incredibly easy to spritz them when measuring, throw em in the grinder and be done.

I've never really read much on the actual effects of water on the coffee flavor itself, just the wonderful lack of static. I don't screw with espresso as I'm at my limit for expensive hobbies. I have in the past and a half gram will make a noticable difference in a shot. Enough to ruin it? Completely subjective.

So the goal is to make your “ideal” shot for the beans you have. Reproducibly. So right off the bat if the ground weight out isn’t equal to the unground weight in (as close and reproducible as possible) then you’ll have to adjust other factors for each shot. Which can quickly become extremely complicated. Especially with static where the amount of loss is going to vary every time.