These brain scans that transmedicalists harp on about simply show that there is no difference between a trans woman and a cis woman on an organic level, but not in the way that they are imagining. There is no "female brain", neurological differences between genders are not absolutes, they are clusters. There are traits more common in women than men, but no two women have the same arrangements of these traits and all of these are found in men as well. It's all just one big, messy spectrum. Trans people fall on the end of the sprectrum that more closely matches our gender identity, not our assigned gender at birth, that's nice i guess, but it's also really, really meaningless and has done nothing to explain an ethiology of transness or to improve trans healthcare. Like, it has literally done zero in that regard, whereas just asking trans people "are you happy with HRT?" produces pretty clear evidence that yes, almost all of us are, gender affirming care is clinically demonstrable to be fucking effective. Deal with it.