this post was submitted on 04 Aug 2026
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A major scientific review is challenging the idea that more protein is always better.

The review, led by pathologist and biomedical researcher Dudley Lamming and published in the journal Cell Press Blue, examined more than 350 studies involving humans, mice, insects, yeast, and other organisms.

The review found that eating less protein, or less of certain amino acids that make up protein, may turn on body processes linked to healthier aging, as well as metabolism, the process by which the body turns food and drinks into energy.

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[–] daychilde@lemmy.world 5 points 1 week ago (2 children)

Well, alright, this is not as annoying as I thought it was going to be. Why? Because I'm on dialysis, and people on dialysis have to eat more protein. I struggle to meet my goals. In fact, I do not meet my goals. Which is irritating.

But I'm also trying to lose weight so I can be considered for a transplant, trying to stay within the limited liquid restrictions, trying to eat enough protein but limit potassium which more protein triggers, limit phosphorous.... there's...... several other things. It's very annoying, especially when I need to cook everything I eat from scratch but sheer fatigue means I'm unable to do so.

Bleh.

So I just needed to vent about that in relation to this study. heh

[–] stringere@sh.itjust.works 1 points 1 week ago (1 children)

What about meal shakes like Huel? I wouldn't recommend a Huel only diet but each serving is 33% of a ton of minerals and vitamins. It might have too much protein in relation to this new information.

[–] daychilde@lemmy.world 1 points 1 week ago (1 children)

Most protein drinks (and I assume meal shakes, but I will look into those now) have lots of potassium. They do make dialysis-friendly protein drinks, although the ones I can find have 10g protein which is not nothing, but considering they take up ¼-⅓ of my daily liquid intake, I don't like them for that reason. heh.

But an otherwise excellent thought <3

[–] stringere@sh.itjust.works 1 points 1 week ago (1 children)

640 mg potassium. 25 grams of plant based protein, though.

[–] daychilde@lemmy.world 1 points 1 week ago (1 children)

From what I can find, the potassium is nearly double that, but maybe my info is outdated. But even with yours, four eggs are about 25g carbs with 275mg potassium. Phosphrous - which I didn't happen to mention - is about the same - but I also take phosphorous binders which helps (in both cases).

However, the annoying thing is that the Huel would be ⅔ of my entire daily fluid allowance - which is 32oz. Which is why I also mentioned the fluid intake, because dialysis-friendly ones tend to be like 12 ounces I think - maybe less, I haven't paid enough attention because I don't use them. heh

But I think you for following up - and while I think it's not useful for me, I think they are useful for some, or maybe even many. :)

[–] stringere@sh.itjust.works 1 points 1 week ago (1 children)

I forgot about the liquid restriction. You could make it with less liquid but it would probably be pretty off-putting texture-wise.

[–] daychilde@lemmy.world 0 points 1 week ago (1 children)

They might - I'll double-check with nutritionalist to make sure, but thank you! <3 :)

[–] jet@hackertalks.com 0 points 1 week ago (1 children)

Carbohydrates drive fat, if you want to lose weight, reduce your carbs or cut them out completely.

This literature survey is basically talking about the virtues of fgf 21 activation, which happens in a high glucose diet with low protein inputs. Inputs. However, they did not look at low glucose diets.

[–] starlinguk@lemmy.world 2 points 1 week ago (1 children)

Carbs are essential for brain function. Which certainly explains keto-fanatics...

[–] skibidi@lemmy.world 2 points 1 week ago (1 children)

Your brain, and all your other cells, can use either glucose or ketones for fuel. They prefer glucose because it is more efficient, but there is no measurable cognitive impairment in those on keto diets - in fact, ketosis has been shown to improve cognitive function in Alzheimer's patients: study.

In general, this isn't an either-or thing. Your body is doing all of these pathways all the time, just the relative degree of them can be shifted depending on what's available in the diet.

[–] jet@hackertalks.com 2 points 1 week ago

Great point, plus the body can make glucose on its own if it's needed, so those keto people still have glucose, it's just 99.9% of the body is burning fat, so there isn't much demand for that glucose.

Bonus fact: the emerging literature is linking long term neurodegenerative diseases (dementia, Alzheimer's, parkinson's, etc) to impaired brain glucose metabolism... I.e the more insulin resistant someone becomes the more energy starved their brains are, but even in those people ketones feed the brain without impairment