this post was submitted on 08 Apr 2026
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[–] mar_k@hexbear.net 7 points 22 hours ago* (last edited 21 hours ago) (2 children)

That said if you're depressed and feel somewhat dependent on weed as a temporary fix, I'd recommend looking into research from the past few years on magic mushrooms. The FDA under Biden literally recognized shrooms as a "breakthrough therapy" treatment for depression. One of the safest (and least addictive) drugs we know of, with a couple states already legalizing shroom therapy for depression. Study after study is showing that just one or two trips (psychoactive doses in a safe, clinical setting, with a tripsitter therapist, relaxing music, and an eyemask) appear far more effective than years of SSRIs and talk therapy. Literally being shown to grow new neural networks and trigger rapid neuroplasticity in the brain

[–] Le_Wokisme@hexbear.net 4 points 21 hours ago (1 children)

have they checked shrooms against shit life syndrome?

[–] mar_k@hexbear.net 2 points 13 hours ago* (last edited 13 hours ago)

Well the bulk of these studies is in people with treatment-resistant major depression where nothing else worked, so pretty much. Also shown to help patients depressed because they have severe debilitating cancer

[–] very_poggers_gay@hexbear.net 2 points 20 hours ago (1 children)

I mean, if someone is depressed and dependent on weed, I'd be hesitant to suggest adding more psychoactive substances. The research on psilocybin and depression is promising (same with research on psilocybin and alcohol use), but AFAIK it is still untested if psilocybin helps with cannabis use disorders or depression+comorbid cannabis use

[–] mar_k@hexbear.net 1 points 14 hours ago* (last edited 6 hours ago)

I wasn't really talking about people will full on cannabis disorder, but even then I can't imagine it making dependency any worse. Just obviously don't be high on weed or take any other substance while tripping, and put time into creating the right set and setting for yourself. (And avoid if you have any history with schizophrenia or delusions)