this post was submitted on 08 Apr 2026
63 points (97.0% liked)
Science
23780 readers
276 users here now
Welcome to Hexbear's science community!
Subscribe to see posts about research and scientific coverage of current events
No distasteful shitposting, pseudoscience, or COVID-19 misinformation.

founded 5 years ago
MODERATORS
you are viewing a single comment's thread
view the rest of the comments
view the rest of the comments
That said if you're depressed and feel somewhat dependent on weed as a temporary fix, I'd recommend looking into research from the past few years on magic mushrooms. The FDA under Biden literally recognized shrooms as a "breakthrough therapy" treatment for depression. One of the safest (and least addictive) drugs we know of, with a couple states already legalizing shroom therapy for depression. Study after study is showing that just one or two trips (psychoactive doses in a safe, clinical setting, with a tripsitter therapist, relaxing music, and an eyemask) appear far more effective than years of SSRIs and talk therapy. Literally being shown to grow new neural networks and trigger rapid neuroplasticity in the brain
have they checked shrooms against shit life syndrome?
Well the bulk of these studies is in people with treatment-resistant major depression where nothing else worked, so pretty much. Also shown to help patients depressed because they have severe debilitating cancer
I mean, if someone is depressed and dependent on weed, I'd be hesitant to suggest adding more psychoactive substances. The research on psilocybin and depression is promising (same with research on psilocybin and alcohol use), but AFAIK it is still untested if psilocybin helps with cannabis use disorders or depression+comorbid cannabis use
I wasn't really talking about people will full on cannabis disorder, but even then I can't imagine it making dependency any worse. Just obviously don't be high on weed or take any other substance while tripping, and put time into creating the right set and setting for yourself. (And avoid if you have any history with schizophrenia or delusions)