this post was submitted on 29 Jan 2026
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And for those who want to get hormones, but are scared of going DIY rather than official: it's in practice just like going the official route, but without the long waiting times and all the gatekeeping.
If you have a GP and endo you trust, and they'd be fine with DIY, it's useful to inform them. Undergo blood tests every three months. Other than that, DIY is just, get the hormones, read the instructions, do.
Guide for what kind of hormone method to use
For the lulz: Is it worth to give a transfem person a paycut of 25% in exchange for paying all HRT and SRS?
Edit: since the first link seems to no longer show the text, see my new comment directly below this one, which posts the text I had in that link.
Replying so I can repost the guide.
I personally use spray, it's like gel but dries much quickier (2 min dry enough, 1 hr to fully dry). But the 'fully dry' is moreso that in that time you'd best not shower yet, that's it.
Dries in 2 min enough to put clothes over the sprayed spot and do your thing. I have a skin that is drier than the Gobi desert, so that also helps.
You'll need to do it daily, but depending on the person, you can have it 1x a day or twice, and up to three doses per time.
Whether or not you want HRT, it's valid. DIY just means you take the meds without a formal prescription. If your situation allows you to do so safely and swiftly, without problems with doctors and/or governments, I'd recommend the official path. Otherwise, DIY is also perfectly valid. Stay safe and aware! If you do HRT, always keep a few months' worth of supply in stock, just in case.
GUIDE TO CHOOSING YOUR MEDICATION PATH (TL:DR; below)
This guide assumes you already have decided to get HRT. It's not meant to replace official advice from affirming and up-to-date doctors, etc. and all that legal stuff.
The following options consist of injections, pellets, patches, gel, spray, sublingual pills, and oral pills.
If you (wish to) carry a child, you may need to change your HRT regimen temporarily.
The following text in this paragraph only applies if you haven't had orchi-/ovariectomy; except for injections and pellets which can work monotherapically, all methods additionally require the hormone blockers for the hormone you want to reduce.
All of the listed HRT methods are safe and work well, it's mainly subtle nuances between them. Which is best, just depends upon your situation and preferences.
If a method, for whatever reason (costs, laws, insurance, transport..), is unavailable for you, then answer as if negative for that method.
1. Do you dislike needles and scars?
Yes -> See question 2
No -> See question 4
2. Do you have sensitive skin?
Yes -> See question 3
No -> See question 5
3. Do you prefer ease of use (although there may be liver/blood issues), or effectiveness?
Ease of use -> Take pills orally (health risk long-term)
Effectiveness -> See question 6
4. Do you want it to be easily available, or for it to be applied less often?
Easily available -> Injections
Apply less often -> Pellet implant
5. Do you want to hide it more easily, or to apply it less often?
Easier to hide -> Gel/Spray; see question 7
Apply less often -> Patches
6. Do you often encounter flammable situations and/or is your skin damaged at the area where you'd apply the hormone?
Yes -> Take pills sublingually (small health risk)
No -> See question 7
7. Do you prefer it to dry quickly, or for it to possibly yield higher hormone levels?
Dries quickier -> Spray
Higher hormone levels -> Gel
TL:DR; If you still don't know which method to use, or feel indifferent - and it is an option -, then I would recommend injections. WillStealYourUsername below me also has some good explanations.
Why that method?
They're the gold standard for combining safety with effect. Consider the following. If you want pills and consume nicotin, you will have to stop with the latter before starting. Patches are pretty visible and can fall off or cause allergic reactions. Spray/gel has to dry for 2-5 minutes, with a cooldown of one hour before showering.Like spray/gel, it bypasses the risk for the liver (sublingual reduces the risk to an extent).
Though they need to be applied more often than pellet implants (which are only once every 6-12 months), they are more affordable and like patches, are not on a daily, but weekly basis. Their doses can be more easily finetuned, and they can work on their own, without blockers being necessary.
Does it have downsides compared to other methods? They hurt a bit (obviously), your hormone levels will spike and fall more sharply, it takes more preparation, and administering it isn't as easy or convenient. But still, injections are the best widely available method. They're the 'jack of trades, master of some', if you will.
Yeah I don't like needles but injections are goat. Anecdotally, it's common to get additional development after switching to injections from pills.
Pellets sound good, but they're often not prescribed.
Also boof your P
The problem with pellets is that they can release the hormones at uneven rates as they dissolve because they aren't perfectly homogeneous. There's also a chance that your body rejects it and forms a fibrous capsule around it that prevents it from releasing the hormones at all.
Interesting, TIL, didn't know that. How common is it?
It's really hard to pin down because of inconsistencies between manufacturers. I've had patients that got pellets and had no effects whatsoever, and some that got way too much because it dissolved too quickly. It also kind of matters who is implanting them and if they know what they're doing. (Pro tip, chiropractors and naturopaths do not know what the fuck they are doing.)