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First-In-Human Trial Of CRISPR Gene-Editing Therapy Safely Lowered Cholesterol, Triglycerides
(finance.yahoo.com)
this post was submitted on 14 Jan 2026
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Is this the first human trial, or just the first officially sanctioned one?
IIRC there was that one guy who experimented on himself and cured his lactose intolerance.
... found it: https://www.youtube.com/watch?v=J3FcbFqSoQY
Nearly 8 years ago.
I feel obligated to mention that he doesn't modify his own genes, he infects himself with a modified bacteria that produces lactase.
you can just eat yogurt to get the same results
First-in-human just means it's the first time that specific therapy is being tested on humans instead of animals (e.g. mice, dogs, monkeys), and the primary objective of the trial is to test that it's safe for use in humans. It doesn't refer to the concept of gene editing or lowering cholesterol.
From the referenced article
What is the point of your comment?
Thought emporium?
Yep thought emporium.
~~But I think the Chinese scientist that experimented on babies did it few years before that even.~~ looks like same year, 2018, and thought emporium published first by 8 months
https://pmc.ncbi.nlm.nih.gov/articles/PMC6724388/
That paper is a wild read