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Anti-Aging Injection Regrows Knee Cartilage and Prevents Arthritis (scitechdaily.com)

submitted 6 days ago by Lemmar@lemmy.today to c/science@lemmy.world

53 comments fedilink hide all child comments

In mice (of course) and human tissue exvivo. Earlier phase 1 studies with 15-PGDH has shown that it is safe and active in healthy volunteers.

Reference: “Inhibition of 15-hydroxy prostaglandin dehydrogenase promotes cartilage regeneration” by Mamta Singla, Yu Xin Wang, Elena Monti, Yudhishtar Bedi, Pranay Agarwal, Shiqi Su, Sara Ancel, Maiko Hermsmeier, Nitya Devisetti, Akshay Pandey, Mohsen Afshar Bakooshli, Adelaida R. Palla, Stuart Goodman, Helen M Blau and Nidhi Bhutani, 27 November 2025, Science. DOI: 10.1126/science.adx6649

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[–] NoTagBacks@lemmy.dbzer0.com 108 points 6 days ago (2 children)

Holy shit. Directly treating the cause of cartilage loss with pill-form treatment in human trials right now. The shit we've been doing with medical science recently is fucking wild.

[–] FlashMobOfOne@lemmy.world 28 points 6 days ago

This summer we'll find out the results of the Galleri test trials in the UK. Another game changer potentially.

[–] veroxii@aussie.zone 17 points 6 days ago (2 children)

Would've been useful before I had my foot cut off. 🤷‍♂️

[–] ChairmanMeow@programming.dev 22 points 6 days ago (1 children)

In 20 years you'll get a pill from the pharmacy to grow a new one 😋

[–] Maeve@kbin.earth 7 points 6 days ago (2 children)

Depends on affordability.

[–] 87Six@lemmy.zip 13 points 6 days ago (1 children)

TONIGHT ON DEAL OR NO DEAL:

you can get this new leg but it will cost you a kidney

[–] MrShankles@reddthat.com 6 points 5 days ago (2 children)

I only need one kidney, AND I can have 3 legs. Deal

[–] Hazy@aussie.zone 2 points 5 days ago

I already have 3 😏

[–] Sciaphobia@sh.itjust.works 1 points 5 days ago

But you have to rename yourself Toejam and befriend someone named Earl.

[–] ChairmanMeow@programming.dev 6 points 6 days ago

It might cost you an arm and a leg.

[–] Kirp123@lemmy.world 5 points 6 days ago

That means you don't need your cartilage regrown.