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Umm... I hate to tell you this but this is propagating some pretty harmful misinformation...
The reactions to medications are actually more closely tied to the hormone balance and body fat distribution of a person than their sex. It's a common issue in the trans community where birth certificates are non-updatable that a doctor will prescribe meds for a person's birth sex but because they are fully transitioned through HRT they get the effects more common to their phenotype presentation. This means that treatment is more commonly in line with their gender identity because of their hormonal medication and other procedures like an orchiectomy that make a person more similar to where they transitioned to then where they transitioned from.
With trans paitents by and large the safer way to behave is to go with the "if it looks like a duck, quacks like a duck and talks like a duck... If you are in a pinch and can't ask them for specifics because they can't talk - treat them like a duck." While a lot of doctors aren't super well versed in trans specific healthcare it remains a huge problem inside the community for trans women particularly being dosed like cis men which often means they respond like cis women to a lot of different things which is on average a little more scary because meds often linger longer than is expected in trans women's tissues just like cis women. Sometimes this causes some cascading problems.
Pharmacology wise the way trans folks react to different medications is still a bit of a frontier science... But dollars to donuts "just treat em like their birth sex and call it a day" is way too simplistic a take. The lived experience and often physical nature of gender do not stay nicely behind a cordon marked "politics". Trans ignorance in healthcare can be very scary for someone whose endocrinologist has informed them what they should be given and treated like and then some hotshot resident could just decide to not listen should the trans person in question be placed in a position where they are in extreme distress and have to self advocate and educate the person caring for them on what may be the worst day of their life.