It’s interesting to have gone the distance without having kids. Very few of my friends who had them seemed to enjoy the experience in the moment, but those few that did really did. Also, a couple of them lost the Russian Roulette and had kids with significant issues that currently can’t be fixed; they are staring down a potential lifetime of dealing with mental health and/or addiction issues in adult children.

I’m fundamentally a risk-taker, but the returns have never seemed worth the commitment and possibility of wildly adverse outcomes, particularly living under the American social and economic models.

Hi, I am from a family with a lot of autoimmune conditions like Crohn's, Ankylosing Spondylitis, MS, and Alzheimer's. My father started to "lose it" in his late 50s, retiring a little early. He lived a long life until early 90s but the last ten years were hard on everyone. But my mother took care of him and we will tried to help.

I was 38 when our child was born. I was very concerned about passing on anything and he probably is going to have Crohn's or IBD.

But here's the thing. All of my family has done our best to live our best lives and yes it isn't the best physical condition at times but we have loved, taken chances, l made mistakes, had laughs, etc. That's worth it.

I've also known people who were ironman triathlon champs having heart attacks.

Only you can decide on kids. That's not why I'm here. I'm here to tell you the chance that you or they might have Alzheimer's doesn't have to be the deciding factor.

Also, there are pilot studies in Alzheimer's vaccines and other treatments.

Have you considered adoption?

If you decide to have kids and choose to have a co-parent, rather being a single parent, choose a co-parent who also wants kids. Having kids with someone who doesn't want them is cursing the kids to be raised by someone who doesn't want them, which can have significant emotional consequences.