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this post was submitted on 19 Aug 2023
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Linux is a family of open source Unix-like operating systems based on the Linux kernel, an operating system kernel first released on September 17, 1991 by Linus Torvalds. Linux is typically packaged in a Linux distribution (or distro for short).
Distributions include the Linux kernel and supporting system software and libraries, many of which are provided by the GNU Project. Many Linux distributions use the word "Linux" in their name, but the Free Software Foundation uses the name GNU/Linux to emphasize the importance of GNU software, causing some controversy.
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Wine almost certainly won't work for an audio interface. A lot of them use kernel drivers. When I got an M2 Mac, my audio interface didn't work. The driver was apparently written in x86 assembly. It actually has tons of issues on ryzen CPUs as well.
After getting my M2 Mac, I upgraded to a more modern interface that doesn't use those types of drivers, so it's far more portable.
I don't have a lot of experience with wine, and the experience that I have is a few years old at this point. But doesn't it have limited compatibility with USB devices? Some audio interface are PCIe cards, but I think the vast majority are USB interfaces. That might make it complicated.
In that case I'd go for a VM, it's chunkier but more complete than Wine will ever be.