If we can't manage to keep Earth's ecosystem thriving to support us, we certainly won't be able to create a new self-sustaining ecosystem elsewhere. And without that, there's no chance of any non-Earth settlement being able to sustain a healthy human society and culture long-term.

Without some serious (currently impossible) terraforming, Mars colonies are limited to deep caves or heavily shielded buildings, no outside to relax, nowhere else to go. Have a look at the list of crimes in Antarctica, a similar situation where people are stuck together, that's not a good environment for mental health, and it will be worse farther away. A Mars colony (edit: or space station) owned by a private company will be a corporate prison, the inhabitants are 100% dependent on that company - who would voluntarily put their lives into the hands of the whims of some narcissistic hoarder with no empathy or regard for workers?